Document Detail

Plastic biliary stent occlusion: factors involved and possible preventive approaches.
MedLine Citation:
PMID:  17456835     Owner:  NLM     Status:  MEDLINE    
Endoscopic biliary stenting is today the most common palliative treatment for patients suffering from obstructive jaundice associated with malignant hepatobiliary tumors or benign strictures. However, recurrent jaundice, with or without cholangitis, is a major complication of a biliary endoprosthesis insertion. Thus, stent removal and replacement with a new one frequently occurs as a consequence of device blockage caused by microbial biofilm growth and biliary sludge accumulation in the lumen. Factors and mechanisms involved in plastic stent clogging arising from epidemiological, clinical and experimental data, as well as the possible strategies to prevent biliary stent failure, will be reviewed and discussed.
Gianfranco Donelli; Emilio Guaglianone; Roberta Di Rosa; Fausto Fiocca; Antonio Basoli
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical medicine & research     Volume:  5     ISSN:  1539-4182     ISO Abbreviation:  Clin Med Res     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-04-25     Completed Date:  2007-11-13     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  101175887     Medline TA:  Clin Med Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  53-60     Citation Subset:  IM    
Department of Technologies and Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.
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MeSH Terms
Bile Duct Diseases
Bile Ducts / pathology
Biliary Tract / pathology*
Biliary Tract Neoplasms / complications,  therapy
Endoscopy / adverse effects
Equipment Contamination
Equipment Design
Equipment Failure
Jaundice, Obstructive / etiology*,  pathology
Prosthesis Implantation / adverse effects
Reg. No./Substance:

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