Document Detail

Plasmodium vivax malaria admissions and risk of mortality in a tertiary-care children's hospital in North India.
MedLine Citation:
PMID:  22824663     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: In 2010, there was an increase in the severity of malaria admissions to Kalawati Saran Children's Hospital, New Delhi and this report describes the morbidity and mortality profile.
METHOD: A retrospective chart review of patients admitted with parasitologically confirmed malaria between January and December 2010.
RESULTS: There were 156 cases: P. vivax 105 (67·3%), P. falciparum 39 (25%) and mixed infections 12 (7·7%). Thrombocytopenia (platelet count <150×10(9)/L) was present in 90 (85·7%) patients with P. vivax mono-infection. There were 91 (58·3%) patients with severe malaria: P. vivax mono-infection 46 (50·5%), P. falciparum mono-infection 35 (38·5%) and mixed 10 (11%). Severe anaemia and severe thrombocytopenia (platelet count <20×10(9)/L) were detected significantly more often in P. falciparum and P. vivax mono-infection, respectively. Complications including cerebral malaria, acute renal failure, shock, acute respiratory distress syndrome (ARDS) and multiple-organ dysfunction syndrome (MODS) were similar in both groups. The mortality rate of around 20% was similar in severe P. vivax and P. falciparum mono-infection. Risk of mortality in vivax malaria was highest in patients with ARDS followed by MODS and shock.
CONCLUSION: Increased morbidity owing to P. vivax malaria was observed and risk of mortality was highest in patients with ARDS and MODS.
Rajni Sharma; Suraj Gohain; Jagdish Chandra; Virendra Kumar; Abhishek Chopra; Sayan Chatterjee; Satinder Aneja; Ashok Kumar Dutta
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Paediatrics and international child health     Volume:  32     ISSN:  2046-9055     ISO Abbreviation:  Paediatr Int Child Health     Publication Date:  2012  
Date Detail:
Created Date:  2012-07-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101582666     Medline TA:  Paediatr Int Child Health     Country:  England    
Other Details:
Languages:  eng     Pagination:  152-7     Citation Subset:  IM    
Lady Hardinge Medical College and Kalawati Saran Children's Hospital, New Delhi, India.
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