| Plasmodium vivax malaria admissions and risk of mortality in a tertiary-care children's hospital in North India. | |
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MedLine Citation:
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PMID: 22824663 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: In 2010, there was an increase in the severity of malaria admissions to Kalawati Saran Children's Hospital, New Delhi and this report describes the morbidity and mortality profile. METHOD: A retrospective chart review of patients admitted with parasitologically confirmed malaria between January and December 2010. RESULTS: There were 156 cases: P. vivax 105 (67·3%), P. falciparum 39 (25%) and mixed infections 12 (7·7%). Thrombocytopenia (platelet count <150×10(9)/L) was present in 90 (85·7%) patients with P. vivax mono-infection. There were 91 (58·3%) patients with severe malaria: P. vivax mono-infection 46 (50·5%), P. falciparum mono-infection 35 (38·5%) and mixed 10 (11%). Severe anaemia and severe thrombocytopenia (platelet count <20×10(9)/L) were detected significantly more often in P. falciparum and P. vivax mono-infection, respectively. Complications including cerebral malaria, acute renal failure, shock, acute respiratory distress syndrome (ARDS) and multiple-organ dysfunction syndrome (MODS) were similar in both groups. The mortality rate of around 20% was similar in severe P. vivax and P. falciparum mono-infection. Risk of mortality in vivax malaria was highest in patients with ARDS followed by MODS and shock. CONCLUSION: Increased morbidity owing to P. vivax malaria was observed and risk of mortality was highest in patients with ARDS and MODS. |
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Authors:
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Rajni Sharma; Suraj Gohain; Jagdish Chandra; Virendra Kumar; Abhishek Chopra; Sayan Chatterjee; Satinder Aneja; Ashok Kumar Dutta |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Paediatrics and international child health Volume: 32 ISSN: 2046-9055 ISO Abbreviation: Paediatr Int Child Health Publication Date: 2012 |
Date Detail:
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Created Date: 2012-07-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101582666 Medline TA: Paediatr Int Child Health Country: England |
Other Details:
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Languages: eng Pagination: 152-7 Citation Subset: IM |
Affiliation:
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Lady Hardinge Medical College and Kalawati Saran Children's Hospital, New Delhi, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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