Document Detail


Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxia.
MedLine Citation:
PMID:  22421613     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We describe the case of a 14-year-old Caucasian male, a resident in the Democratic Republic of the Congo, who was observed in Portugal with severe Plasmodium falciparum malaria with high-level parasitemia and severe thrombocytopenia. The course was complicated by bilateral sixth cranial nerve palsy during acute malaria, followed by the appearance of delayed cerebellar ataxia during the recovery phase. This occurred after successful treatment with quinine plus doxycycline over seven days. Different levels of thrombocytopenia and C-reactive protein were observed during both neurologic events in the presence of HRP-2 positive tests for Plasmodium falciparum antigen. The patient recovered completely after three months.
Authors:
Vitor Duque; Diana Seixas; Conceição Ventura; Saraiva Da Cunha; António Meliço-Silvestre
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Publication Detail:
Type:  Journal Article     Date:  2012-03-12
Journal Detail:
Title:  Journal of infection in developing countries     Volume:  6     ISSN:  1972-2680     ISO Abbreviation:  J Infect Dev Ctries     Publication Date:  2012  
Date Detail:
Created Date:  2012-03-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101305410     Medline TA:  J Infect Dev Ctries     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  290-4     Citation Subset:  IM    
Affiliation:
Serviço de Infecciosas, Hospitais da Universidade de Coimbra, EPE, Portugal. duque.vitor@gmail.com.
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