Document Detail


Plasma renin activity, angiotensin II, and aldosterone during intense heat stress.
MedLine Citation:
PMID:  965299     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Plasma renin activity (PRA), angiotensin II, and aldosterone levels, arterial blood pressure, and heart rate of six male students were investigated during and after heat stress in a sauna bath. Increased PRA, angiotensin II, and aldosterone levels were found both during and after sauna. The greatest mean increases in PRA (94.9 +/- 10.4% SE, P less than 0.005) and angiotensin II (196 +/- 54.7% SE, P less than 0.02) were observed at the end of the heat stress (at 20 min), and that in plasma aldosterone (505 +/- 209% SE, P less than 0.02) 30 min after the sauna. The heart rate roughly doubled during the heat stress and there was a transient increase followed by a decrease in systolic blood pressure and a decrease in diastolic blood pressure. This study demonstrates that intense heat stress can cause remarkable changes in the three main components of the renin-angiotensin-aldosterone system.
Authors:
K J Kosunen; A J Pakarinen; K Kuoppasalmi; H Adlercreutz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of applied physiology     Volume:  41     ISSN:  0021-8987     ISO Abbreviation:  J Appl Physiol     Publication Date:  1976 Sep 
Date Detail:
Created Date:  1976-12-01     Completed Date:  1976-12-01     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0376576     Medline TA:  J Appl Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  323-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aldosterone / blood*
Angiotensin II / blood*
Blood Pressure
Blood Proteins
Creatinine / blood
Heart Rate
Hot Temperature*
Humans
Leukocyte Count
Male
Renin / blood*
Sodium / blood
Stress, Physiological / blood*,  physiopathology
Chemical
Reg. No./Substance:
0/Blood Proteins; 11128-99-7/Angiotensin II; 52-39-1/Aldosterone; 60-27-5/Creatinine; 7440-23-5/Sodium; EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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