Document Detail


Plasma and red blood cell total phospholipid fatty acid status of nonpregnant female Vervet monkeys (Cercopithecus aethiops) on a high carbohydrate maintenance diet.
MedLine Citation:
PMID:  9926979     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nonhuman primates are of interest as models of human physiology to study the effect of multiple pregnancies on birth weight. Reference plasma and red blood cell (RBC) total phospholipids fatty acids were established in nonpregnant breeding female Vervet monkeys. Twenty-three clinically healthy nonpregnant Vervet monkeys (Cercopithecus aethiops), contained in a controlled closed environment and consuming a high carbohydrate diet (68 E%) that contained 20 E% fat and 12 E% protein were sampled for blood during a cross-sectional study. A low intake of omega3 fatty acids was reflected by a high omega6/omega3 ratio (66:1) of the diet. Inverse relations were seen between plasma and RBC total phospholipid fatty acids, 18:2omega6, 20:3omega6, and 20:4omega6, which suggested selective incorporation in membranes. Low levels of 20:5omega3 and 22:6omega3 of plasma and RBC total phospholipids render Vervet monkeys as ideal subjects to study the effect of omega3 fatty acid supplementation on pregnancy outcomes.
Authors:
H Y Tichelaar; P J van Jaarsveld; C M Smuts; M Marais; M C Mdhluli; M Kruger; A J Benadé
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of medical primatology     Volume:  27     ISSN:  0047-2565     ISO Abbreviation:  J. Med. Primatol.     Publication Date:  1998 Oct 
Date Detail:
Created Date:  1999-03-24     Completed Date:  1999-03-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0320626     Medline TA:  J Med Primatol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  240-3     Citation Subset:  IM    
Affiliation:
National Research Programme for Nutritional Intervention, Tygerberg, South Africa.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cercopithecus aethiops / physiology
Dietary Carbohydrates / administration & dosage*
Erythrocytes / chemistry
Fatty Acids / blood*
Female
Humans
Nutritional Requirements
Phospholipids / blood*
Pregnancy
Pregnancy Outcome
Reference Values
Chemical
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Fatty Acids; 0/Phospholipids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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