Document Detail


Plasma nitric oxide and left ventricular function in rabbits after cardiac lymphatic obstruction.
MedLine Citation:
PMID:  21342136     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
This study was designed to investigate the effect of cardiac lymphatic obstruction on plasma nitric oxide (NO) and left ventricular function. The plasma NO was measured in study group (n=21) and control group rabbits (n=12) before, and 3, 7, 14, 30 and 90 days after the obstruction of cardiac lymphatic vessels. Left ventricular ejection fraction was measured with echocardiography. There was a significant reduction in the left ventricular ejection fraction following the lymphatic obstruction (0.72±0.02 vs. 0.61±0.02, p<0.01). Plasma NO in the control group remained unchanged during the observation period (54.2±4.4 vs. 52.0±4.2 μmol/L, p>0.05). In the study group, there was a small but significant increase in the plasma NO on day 3, 7 and 14 following the lymphatic obstruction (52.3±4.1 vs. 73.4±5.9 μmol/L, p<0.01). The plasma NO returned to the baseline levels on day 30 but reduced to 44.9±3.6 μmol/L on 90 days after the lymphatic obstruction (p<0.05). In conclusion, cardiac lymphatic obstruction was associated with a significant reduction in left ventricular function. It was also associated with an increase in the plasma NO in the first 2 weeks but there was a significant reduction in the NO levels three months after the lymphatic obstruction.
Authors:
Ying-Li Wang; Xiao-Hua Wang; Ye Jin; De-Gui Kong; Le-Xin Wang
Related Documents :
19054036 - Intraoperative real time three-dimensional transesophageal echocardiographic measuremen...
15473466 - Heyde's syndrome: a review.
2070096 - Echocardiographic changes in patients with heterozygous and homozygous familial hyperch...
7245496 - Recovery of cardiac function with total transapical left ventricular bypass.
20653086 - Incidence and outcomes of out-of-hospital cardiac arrest with shock-resistant ventricul...
23804866 - Serum cardiac troponin t in asphyxiated term neonates delivered at two teaching hospita...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences     Volume:  11     ISSN:  1840-4812     ISO Abbreviation:  Bosn J Basic Med Sci     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101200947     Medline TA:  Bosn J Basic Med Sci     Country:  Bosnia and Hercegovina    
Other Details:
Languages:  eng     Pagination:  17-9     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Liaocheng People's Hospital and Liaocheng Clinical School of Taishan Medical University, No. 67 Dong Chang Xi Road, Liaocheng, Shandong Province, 252000, PR China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Hypoglycaemic action of stevioside and ? barley and brewer's yeast based preparation in the experime...
Next Document:  HLA Association in SLE patients from Lahore-Pakistan.