| Plasma n-3 Polyunsaturated Fatty Acids are negatively associated with obesity. | |
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MedLine Citation:
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PMID: 19454127 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The objective of the present study was to investigate the relationship between plasma n-3 PUFA composition and weight status. A total of 124 adults, stratified by weight status: healthy weight (n 21), overweight (n 40) and obese (n 63) were recruited. Fasting blood samples, anthropometric measures and body composition were collected. Plasma fatty acid composition was determined by GC. BMI, waist circumference and hip circumference were inversely correlated with n-3 PUFA, EPA and DHA (P < 0.05 for all) in the obese group. Obese individuals had significantly lower plasma concentrations of total n-3 PUFA, compared with healthy-weight individuals (4.53 (SD 1.11) v. 5.25 (SD 1.43) %). When subjects were pooled and stratified into quartiles of total n-3 PUFA, a significant inverse trend was found for BMI (P = 0.002), waist circumference and hip circumference (P = 0.01 and P < 0.001 respectively). Higher plasma levels of total n-3 PUFA are associated with a healthier BMI, waist circumference and hip circumference. Our findings suggest that n-3 PUFA may play an important role in weight status and abdominal adiposity. |
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Authors:
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Michelle Micallef; Irene Munro; Melinda Phang; Manohar Garg |
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Publication Detail:
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Type: Journal Article Date: 2009-05-19 |
Journal Detail:
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Title: The British journal of nutrition Volume: 102 ISSN: 1475-2662 ISO Abbreviation: Br. J. Nutr. Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-10-30 Completed Date: 2009-12-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: England |
Other Details:
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Languages: eng Pagination: 1370-4 Citation Subset: IM |
Affiliation:
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Nutraceuticals Research Group, School of Biomedical Sciences, University of Newcastle, Callaghan, NSW, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Anthropometry / methods Body Mass Index Fatty Acids, Omega-3 / blood* Female Hip / pathology Humans Male Middle Aged Obesity / blood*, pathology, physiopathology Overweight / blood, pathology, physiopathology Waist Circumference Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids, Omega-3 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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