| Plasma lipoproteins are important components of the immune system. | |
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MedLine Citation:
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PMID: 20377753 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Plasma lipoproteins (VLDL, LDL, Lp[a] and HDL) function primarily in lipid transport among tissues and organs. However, cumulative evidence suggests that lipoproteins may also prevent bacterial, viral and parasitic infections and are therefore a component of innate immunity. Lipoproteins can also detoxify lipopolysaccharide and lipoteichoic acid. Infections can induce oxidation of LDL, and oxLDL in turn plays important anti-infective roles and protects against endotoxin-induced tissue damage. There is also evidence that apo(a) is protective against pathogens. Taken together, the evidence suggests that it might be valuable to introduce the concept that plasma lipoproteins belong in the realm of host immune response. |
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Authors:
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Runlin Han |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Microbiology and immunology Volume: 54 ISSN: 0385-5600 ISO Abbreviation: Microbiol. Immunol. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-09 Completed Date: 2010-07-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7703966 Medline TA: Microbiol Immunol Country: Japan |
Other Details:
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Languages: eng Pagination: 246-53 Citation Subset: IM |
Affiliation:
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Research Center of Plasma Lipoprotein Immunology, College of Animal Medicine, Inner Mongolia Agricultural University, 306 Zhaowuda Road, Huhhot, 010018, China. runlinhan@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bacterial Infections
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immunology Humans Immunity, Innate* Lipoproteins / blood*, immunology Parasitic Diseases / immunology Virus Diseases / immunology |
| Chemical | |
Reg. No./Substance:
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0/Lipoproteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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