Document Detail

Plasma lipids during extracorporeal circulation.
MedLine Citation:
PMID:  1177479     Owner:  NLM     Status:  MEDLINE    
Total lipids, lipid classes, and per cent composition of fatty acids were investigated in plasma and stored subcutaneous fats of 19 subjects undergoing extracorporeal circulation (ECC). The tests were made before and 3, 20, 40, and 60 minutes after ECC was started. Hemodilution caused a general fall in total lipids and lipid classes. Evaluation of the lipid classes as percentages of the total lipids assumed to be 100 per cent allow the lipid variation due to hemodilution to be disregarded. A linear correlation between an increase in free fatty acids (FFA) and a decrease in triglycerides can thus be observed. This has been attributed to action of the lipase lipoproteic (LLP) activity stimulated by heparin, which is usually employed in ECC hemodilution. The hypothesis that FFA's are mobilized from stored subcutaneous fats was discounted.
P Ghirardi; A Marzo; C Rossi; E Respighi; B Brusoni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of thoracic and cardiovascular surgery     Volume:  70     ISSN:  0022-5223     ISO Abbreviation:  J. Thorac. Cardiovasc. Surg.     Publication Date:  1975 Oct 
Date Detail:
Created Date:  1975-12-20     Completed Date:  1975-12-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376343     Medline TA:  J Thorac Cardiovasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  661-5     Citation Subset:  AIM; IM    
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MeSH Terms
Cholesterol / blood
Extracorporeal Circulation*
Fatty Acids, Nonesterified / blood
Lipids / blood*
Middle Aged
Phospholipids / blood
Time Factors
Triglycerides / blood
Reg. No./Substance:
0/Fatty Acids, Nonesterified; 0/Lipids; 0/Phospholipids; 0/Triglycerides; 57-88-5/Cholesterol

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