Document Detail

Plasma lipid effects of three common vegetable oils in reduced-fat diets of free-living adults.
MedLine Citation:
PMID:  8030596     Owner:  NLM     Status:  MEDLINE    
We compared plasma lipid changes due to the polyunsaturated fatty acids (PUFAs) in partially hydrogenated soybean oil, corn oil, and sunflower oil fed in reduced-fat diets (22-26% of total energy). Each oil was the dominant fat in isoenergetic diets of centrally prepared foods consumed by 26 male and 35 female normolipidemic, free-living individuals. Test diets were consumed double-blind, alternating with self-selected diets for 5 wk each. The ranges of proportions of total fat were: 4.7-9.7% polyunsaturated fat, 8.9-14.2% monounsaturated fat and 5.4-7.4% saturated fat. All three diets lowered (P < 0.0001) total cholesterol (11%), LDL cholesterol (13%), and HDL cholesterol (10%), without triglyceride changes. We conclude that PUFAs at approximately 6% of total energy result in clinically relevant plasma cholesterol-lowering and that the proportion of polyunsaturated fat must be an important consideration when planning reduced-fat, reduced-saturated-fat diets.
W Insull; A Silvers; L Hicks; J L Probstfield
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  60     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1994-08-11     Completed Date:  1994-08-11     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  195-202     Citation Subset:  AIM; IM    
Department of Medicine, Baylor College of Medicine, Methodist Hospital, Houston, TX.
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MeSH Terms
Cholesterol / blood*
Cholesterol, HDL / blood
Cholesterol, LDL / blood
Corn Oil / administration & dosage
Dietary Fats, Unsaturated / administration & dosage*
Double-Blind Method
Middle Aged
Plant Oils / administration & dosage*
Sex Characteristics
Soybean Oil / administration & dosage
Triglycerides / blood
Grant Support
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Dietary Fats, Unsaturated; 0/Plant Oils; 0/Triglycerides; 57-88-5/Cholesterol; 8001-21-6/sunflower seed oil; 8001-22-7/Soybean Oil; 8001-30-7/Corn Oil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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