Document Detail

Plasma lipid and apolipoprotein levels in children hereditarily predisposed to coronary heart disease.
MedLine Citation:
PMID:  3394509     Owner:  NLM     Status:  MEDLINE    
Plasma lipids and apoproteins A-I, A-II and B levels were measured in 125 children whose fathers had coronary atherosclerosis (paternal coronary heart disease group), in 172 children with blood pressure lability and in 154 children selected at random from a representative subsample (reference). The paternal coronary heart disease group had, compared with the reference group, lower levels of high density lipoprotein cholesterol and apoprotein A-I, higher levels of low density lipoprotein cholesterol, triglycerides and apoprotein B, and also a higher ratio of apoprotein B to apoprotein A-I. The paternal coronary heart disease group subjects with blood pressure lability had the most pronounced changes in the lipoprotein spectrum, which were similar to atherogenic changes in the lipoprotein profile, characteristic of patients with coronary atherosclerosis.
N Perova; H Aingorn; V Metelskaya; T Dorofeeva; N Belokonj
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica Scandinavica     Volume:  77     ISSN:  0001-656X     ISO Abbreviation:  Acta Paediatr Scand     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-08-25     Completed Date:  1988-08-25     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0000211     Medline TA:  Acta Paediatr Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  559-62     Citation Subset:  IM    
Institute of Preventive Cardiology, USSR Cardiology Research Center, Moscow.
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MeSH Terms
Apolipoproteins / blood*
Apolipoproteins A / blood
Apolipoproteins B / blood
Blood Pressure
Cholesterol, LDL / blood
Coronary Artery Disease / blood,  genetics*
Lipids / blood*
Triglycerides / blood
Reg. No./Substance:
0/Apolipoproteins; 0/Apolipoproteins A; 0/Apolipoproteins B; 0/Cholesterol, LDL; 0/Lipids; 0/Triglycerides

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