| Plasma levels and urinary excretion of amino acids by subjects with renal calculi. | |
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MedLine Citation:
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PMID: 19787430 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Plasma levels and urinary amino acid excretions were estimated by high-performance liquid chromatography in 15 control subjects and 36 stone formers (SFs) classified according to the stone type: (1) 22 cases with calcium oxalate stones; (2) four cases with pure uric acid stones; (3) 10 cases with magnesium-ammonium phosphate stones, either pure or mixed with apatite. Some types of stones (namely oxalate and uric acid calculi) are mainly formed as a result of a metabolic deficiency that may affect the amino acid metabolism, and thus may be reflected in the urinary amino acid pattern. Data demonstrated clearly that there is a general tendency towards decreased amino acid excretions in all SFs with all types of stones. As a whole, one can observe a higher percentage of patients with calcium oxalate and phosphate calculosis, who have low urine excretions of amino acids; about 50% are the SFs with lower urine excretion of serine, glycine, taurine and i-leucine; the high percentage of patients with CaOX calculi shows lower urine excretions of tyrosine and ornithine. |
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Authors:
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Stoyanka Slavcheva Atanassova; P Panchev; M Ivanova |
Publication Detail:
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Type: Journal Article; Review Date: 2009-09-29 |
Journal Detail:
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Title: Amino acids Volume: 38 ISSN: 1438-2199 ISO Abbreviation: Amino Acids Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-04-28 Completed Date: 2010-08-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9200312 Medline TA: Amino Acids Country: Austria |
Other Details:
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Languages: eng Pagination: 1277-82 Citation Subset: IM |
Affiliation:
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Department of Urology, Alexandrov's University Hospital, Medical University, G. Sofiisky Blvd 1, 1431, Sofia, Bulgaria. stoyana_atanassova@abv.bg |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Amino Acids / blood, metabolism*, urine Apatites / metabolism Calcium Oxalate / metabolism Chromatography, High Pressure Liquid Female Humans Kidney Calculi / blood, metabolism*, urine Magnesium Compounds / metabolism Male Middle Aged Phosphates / metabolism Uric Acid / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Apatites; 0/Magnesium Compounds; 0/Phosphates; 15490-91-2/struvite; 25454-23-3/Calcium Oxalate; 69-93-2/Uric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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