Document Detail

Plasma levels of homocysteine in patients with white-coat hypertension.
MedLine Citation:
PMID:  15605659     Owner:  NLM     Status:  MEDLINE    
Elevated levels of plasma homocysteine (Hcy) is an independent risk factor for cardiovascular diseases. The risk profile of white-coat hypertension (WCHT) is not yet completely clear. In this study, we aim to determine the levels of plasma Hcy in a group of patients with WCHT, and to obtain clinical results by comparing WCHT group with hypertensive and healthy groups. Age, sex and body mass index were matched for 15 normal subjects, 15 patients with WCHT and 15 patients with essential hypertension, and they were included in the study. We measured levels of plasma Hcy in all groups. Levels of plasma Hcy were significantly higher in patients with sustained hypertension than in WCHT group (p = 0.03). They were also significantly higher in patients with WCHT than in control group (p = 0.02). Our data suggest that WCHT subjects are at an increased cardiovascular risk, although this was lower than the risk in patients with sustained hypertension.
E Coban; M Ozdoğan; C Ermiş
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of clinical practice     Volume:  58     ISSN:  1368-5031     ISO Abbreviation:  Int. J. Clin. Pract.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-12-20     Completed Date:  2005-03-18     Revised Date:  2007-02-14    
Medline Journal Info:
Nlm Unique ID:  9712381     Medline TA:  Int J Clin Pract     Country:  England    
Other Details:
Languages:  eng     Pagination:  997-9     Citation Subset:  IM    
Faculty of Medicine, Department of Internal Medicine, Akdeniz University, Arapsuyu, Antalya, Turkey.
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MeSH Terms
Biological Markers / blood
Homocysteine / blood*
Hypertension / blood*
Middle Aged
Risk Factors
Reg. No./Substance:
0/Biological Markers; 454-28-4/Homocysteine

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