Document Detail


Plasma levels of apolipoprotein M in normal and complicated pregnancy.
MedLine Citation:
PMID:  20804348     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Apolipoprotein M (apoM) is mainly associated with high-density lipoprotein in human plasma. Despite several studies suggesting apoM as an anti-atherogenic, its function is not yet fully understood. Plasma apoM was measured in normal pregnancies at four different gestational ages and in the postpartum period to investigate whether the concentration of apoM changes during pregnancy. In addition, apoM was measured at 13 weeks in women who subsequently developed preeclampsia, gestational diabetes, recurrent miscarriage, or small-for-gestational age babies, and in women with uncomplicated pregnancies. The plasma concentrations of apoM increased during pregnancy to reach highest levels in the postpartum period. Thus, plasma apoM in non-pregnant women was around 0.77 micromol/l, 0.88 micromol/l at 40 gestational weeks, and 1.05 micromol/l in the postpartum period (p < 0.0001). No differences in plasma concentrations of apoM were found among the studied pregnancy complications.
Authors:
Josefin Ahnström; Pelle G Lindqvist; Ursula Walle; Björn Dahlbäck
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  89     ISSN:  1600-0412     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-31     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  England    
Other Details:
Languages:  eng     Pagination:  1214-7     Citation Subset:  IM    
Affiliation:
Department of Laboratory Medicine, University Hospital, Lund University, Malmö, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Adult
Apolipoproteins / blood*
Case-Control Studies
Cross-Sectional Studies
Female
Humans
Longitudinal Studies
Postpartum Period / blood
Pregnancy / blood*
Pregnancy Complications / blood*
Chemical
Reg. No./Substance:
0/APOM protein, human; 0/Apolipoproteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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