| Plasma levels of apolipoprotein M in normal and complicated pregnancy. | |
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MedLine Citation:
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PMID: 20804348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Apolipoprotein M (apoM) is mainly associated with high-density lipoprotein in human plasma. Despite several studies suggesting apoM as an anti-atherogenic, its function is not yet fully understood. Plasma apoM was measured in normal pregnancies at four different gestational ages and in the postpartum period to investigate whether the concentration of apoM changes during pregnancy. In addition, apoM was measured at 13 weeks in women who subsequently developed preeclampsia, gestational diabetes, recurrent miscarriage, or small-for-gestational age babies, and in women with uncomplicated pregnancies. The plasma concentrations of apoM increased during pregnancy to reach highest levels in the postpartum period. Thus, plasma apoM in non-pregnant women was around 0.77 micromol/l, 0.88 micromol/l at 40 gestational weeks, and 1.05 micromol/l in the postpartum period (p < 0.0001). No differences in plasma concentrations of apoM were found among the studied pregnancy complications. |
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Authors:
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Josefin Ahnström; Pelle G Lindqvist; Ursula Walle; Björn Dahlbäck |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta obstetricia et gynecologica Scandinavica Volume: 89 ISSN: 1600-0412 ISO Abbreviation: Acta Obstet Gynecol Scand Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-31 Completed Date: 2010-09-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: England |
Other Details:
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Languages: eng Pagination: 1214-7 Citation Subset: IM |
Affiliation:
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Department of Laboratory Medicine, University Hospital, Lund University, Malmö, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Apolipoproteins / blood* Case-Control Studies Cross-Sectional Studies Female Humans Longitudinal Studies Postpartum Period / blood Pregnancy / blood* Pregnancy Complications / blood* |
| Chemical | |
Reg. No./Substance:
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0/APOM protein, human; 0/Apolipoproteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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