Document Detail


Plasma levels of B-type natriuretic Peptide in patients with unstable angina pectoris or acute myocardial infarction: prognostic significance and therapeutic implications.
MedLine Citation:
PMID:  17626979     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Plasma B-type natriuretic peptide (BNP) levels were obtained from 146 patients with unstable angina pectoris, non-ST-segment elevation myocardial infarction (MI), or ST-segment elevation MI to determine their value in predicting the presence of new heart failure, recurrent MI or ischemia, or death 1 month after the index event. Patients with elevated plasma BNP levels (>80 pg/mL) had a significantly higher incidence of new heart failure and all-cause mortality than those with a normal plasma BNP level (<or=80 pg/mL). Early revascularization with percutaneous intervention or coronary artery bypass grafting significantly reduced the incidence of new heart failure and all-cause mortality in patients with an elevated plasma BNP level, but had no effect on individual outcomes in the normal plasma BNP subgroup.
Authors:
Waqas Ahmed; Saman Zafar; Ali Y Alam; Naveed Ahktar; Mumtaz A Shah; Martin A Alpert
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Angiology     Volume:  58     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:    2007 Jun-Jul
Date Detail:
Created Date:  2007-07-13     Completed Date:  2007-08-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  269-74     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Shifa International Hospital, Islamabad, Pakistan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angina, Unstable / blood,  complications,  diagnosis*,  mortality,  therapy
Angioplasty, Transluminal, Percutaneous Coronary
Biological Markers / blood
Cardiac Output, Low / blood,  etiology*,  mortality
Coronary Angiography
Coronary Artery Bypass
Female
Humans
Incidence
Male
Middle Aged
Myocardial Infarction / blood,  complications,  diagnosis*,  mortality,  therapy
Myocardial Ischemia / blood,  etiology*,  mortality
Natriuretic Peptide, Brain / blood*
Predictive Value of Tests
Prospective Studies
Recurrence
Risk Assessment
Time Factors
Treatment Outcome
Troponin T / blood
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Troponin T; 114471-18-0/Natriuretic Peptide, Brain

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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