Document Detail


Plasma leakage of oxygenators in ECMO depends on the type of oxygenator and on patient variables.
MedLine Citation:
PMID:  15742307     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study was conducted to identify the causes of plasma leakage of oxygenators in extra corporeal membrane oxygenation (ECMO). From 1996 through 2002, 91 oxygenators were used in 62 patients undergoing ECMO for respiratory and/or cardiac failure. Several types of oxygenators were used (Medtronic Maxima, Minima, PRF, Medos Hilite). Patient variables and variables related to the ECMO set-up were analysed for their relationship with oxygenator failure by a time related multiple regression analysis (Cox). Oxygenator failure occurred in 26% of the cases. The analysis identified the type of oxygenator (p=0.0016), younger patient age (p=0.04) and the number of oxygenators used (p=0.03) as the independent significant risk factors. The type of oxygenator used has the most overwhelming effect (significantly less leakage with the Medos Hilite). In conclusion, leakage of oxygenators is predominantly caused by the type of oxygenator used. Patient variables (younger age and the number of oxygenators used in one patient) are also significant and allude to an inflammatory process as underlying mechanism of plasma leakage.
Authors:
B Meyns; L Vercaemst; E Vandezande; H Bollen; D Vlasselaers
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The International journal of artificial organs     Volume:  28     ISSN:  0391-3988     ISO Abbreviation:  Int J Artif Organs     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-03-02     Completed Date:  2005-06-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802649     Medline TA:  Int J Artif Organs     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  30-4     Citation Subset:  IM    
Affiliation:
Department of Cardiac Surgery, Catholic University, Leuven, Belgium. Bart.Meyns@uz.kuleuven.ac.be
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Aged
Cardiac Output, Low / therapy
Child
Child, Preschool
Equipment Design
Equipment Failure
Extracorporeal Membrane Oxygenation / instrumentation*
Female
Humans
Infant
Male
Middle Aged
Oxygenators, Membrane* / classification
Plasma
Proportional Hazards Models
Respiratory Insufficiency / therapy
Retreatment
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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