Document Detail

Plasma insulin and blood pressure response to oral glucose tolerance test in young borderline hypertensives.
MedLine Citation:
PMID:  8412338     Owner:  NLM     Status:  MEDLINE    
In order to evaluate whether borderline hypertension might be associated with hyperinsulinaemia, twenty non-obese borderline hypertensives and twenty matched normotensives underwent a standard oral glucose tolerance test and 24-h ambulatory blood pressure monitoring. Blood pressure, plasma glucose and insulin were measured at fasting and 15, 30, 60, 120 and 180 minutes after glucose load. Fasting plasma insulin was significantly higher in borderline hypertensives in comparison to normotensives (16.6 +/- 6.9 vs 12.4 +/- 4.2 mU/l; P < 0.05). Plasma insulin response estimated by the positive incremental area under the curve did not differ significantly between two groups but borderline hypertensives showed a larger interindividual difference. Decrease of systolic blood pressure after glucose load was significantly greater in borderline hypertensive subjects. Furthermore, blood pressure and plasma insulin relationship was different in borderline hypertensives compared to normotensives.
K Narkiewicz; A Rynkiewicz; J Furmański; J Gan; E Narwojsz; L Bieniaszewski; B Krupa-Wojciechowska
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Materia medica Polona. Polish journal of medicine and pharmacy     Volume:  25     ISSN:  0025-5246     ISO Abbreviation:  Mater Med Pol     Publication Date:    1993 Jan-Mar
Date Detail:
Created Date:  1993-11-09     Completed Date:  1993-11-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0236526     Medline TA:  Mater Med Pol     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  23-6     Citation Subset:  IM    
Second Department of Internal Diseases, Medical Academy, Gdańsk, Poland.
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MeSH Terms
Blood Glucose / analysis*
Blood Pressure*
Glucose Tolerance Test
Hypertension / blood*,  physiopathology
Insulin / blood*
Reg. No./Substance:
0/Blood Glucose; 11061-68-0/Insulin

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