Document Detail


Plasma high-density lipoprotein cholesterol comparisons in black and white populations. The Lipid Research Clinics Program Prevalence Study.
MedLine Citation:
PMID:  7418150     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
High-density lipoprotein (HDL) cholesterol distributions were compared among 191 black and 1341 white males and 233 black and 1088 white females, ages 5-44 years, examined in five of the Lipid Research Clinic (LRC) population-based surveys. Mean HDL cholesterol was higher in blacks than whites in each 5-year age group for males and in seven of the eight age groups for females. The black-white mean HDL cholesterol difference was greater for males than females at each age studied. Mean HDL cholesterol was 4.8 mg/dl higher in black than white males ages 5-19 years, after statistical adjustment for age, Quetelet index and plasma total cholesterol differences between blacks and whites (p < 0.001); mean HDL cholesterol was 9.5 mg/dl higher in black than white adult males ages 20-44 years. Adjustment for levels of plasma triglyceride, which were lower in blacks than whites, reduced but did not eliminate the magnitude of the statistical significance in black-white differences: The adjusted means were 2.9 mg/dl higher in black children and 7.9 mg/dl higher in black adults. The finding of higher levels of HDL cholesterol in black males persisted after additional adjustment for alcohol consumption, smoking and educational levels. Adult U.S. black males have lower and black females have higher coronary heart disease mortality rates than their white peers. The magnitude of the black-white difference in HDL cholesterol for males in the LRC studies was within the range associated with coronary heart disease incidence reported in other studies.
Authors:
H A Tyroler; C J Glueck; B Christensen; P O Kwiterovich
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Circulation     Volume:  62     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1980 Nov 
Date Detail:
Created Date:  1980-12-16     Completed Date:  1980-12-16     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  IV99-107     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
African Continental Ancestry Group
Aging
Analysis of Variance
Child
Child, Preschool
European Continental Ancestry Group
Female
Humans
Lipids
Lipoproteins, HDL / blood*
Lipoproteins, LDL / blood
Lipoproteins, VLDL / blood
Male
Research
Triglycerides / blood
Grant Support
ID/Acronym/Agency:
N01-HV1-2156-L/HV/NHLBI NIH HHS; N01-HV1-2160-L/HV/NHLBI NIH HHS; N01-HV2-2914-L/HV/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Lipids; 0/Lipoproteins, HDL; 0/Lipoproteins, LDL; 0/Lipoproteins, VLDL; 0/Triglycerides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Plasma high-density lipoprotein cholesterol, total cholesterol and triglyceride levels in 17-year-ol...
Next Document:  Effects of respiration and posture on paroxysmal supraventricular tachycardia.