| Plasma high-density-lipoprotein cholesterol levels during long-term use of an oral contraceptive in Nigerian women. | |
| | |
MedLine Citation:
|
PMID: 7171504 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Total and high-density lipoprotein (HDL) cholesterol were estimated in 131 blood samples obtained from women who had been taking the oral contraceptive Noriday 1 + 50Fe (one packet contains 21 tablets of 1 mg of norethindrone + 0.05 mg of mestranol, and 7 of 75 mg of ferrous fumarate) for 1-60 months. Thirty five women who had never used oral contraception (OC) formed the control group. There was a significantly higher mean HDL cholesterol level, and HDL cholesterol/total cholesterol ratio but not total cholesterol level in the women who had been using OC for 19-60 months. The values in women who had been using OC for 1-18 months were not significantly different from those in the control group. The increase in the HDL cholesterol level may not depend on the oestrogen content of the oral contraceptive but on the duration of its intake. Total and high-density lipoprotein (HDL) cholesterol were estimated in 131 blood samples obtained from women who had been taking the oral contraceptive (OC) Noriday 1+50Fe (1 packet contains 21 tablets of 1 mg of norethindrone + 0.05 mg of mestranol, and 7 of 75 mg of ferrous fumarate) for 1-60 months. 35 women who had never used OCs formed the control group. There was a significantly higher mean HDL cholesterol level and HDL cholesterol/total cholesterol ratio but not total cholesterol level in the women who had been using OCs for 19-60 months. Values in women who had been using OCs for 1-18 months were not significantly different from the control group. The increase in the HDL cholesterol level may not depend on the estrogen content of the OC but on the duration of its intake. This increase may be beneficial as HDL-cholesterol has been reported to have an anti-atherogenic effect. |
| | |
Authors:
|
G O Taylor; E O Agbedana; O A Ojo |
Related Documents
:
|
525434 - Risk factors for myocardial infarction in the stockholm prospective study. a 14-year fo... 11053704 - Evidence that triglycerides are an independent coronary heart disease risk factor. 7586554 - Serum concentrations of apolipoprotein a-i, apolipoprotein b, and lipoprotein(a) in a p... 3591604 - Serum lipids and lipoproteins after myocardial infarction: associations with cardiovasc... 17966264 - Workplace hazards to women's reproductive health. 2618604 - Mobiluncus and clue cells as predictors of pid after first-trimester abortion. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: British journal of obstetrics and gynaecology Volume: 89 ISSN: 0306-5456 ISO Abbreviation: Br J Obstet Gynaecol Publication Date: 1982 Nov |
Date Detail:
|
Created Date: 1983-02-14 Completed Date: 1983-02-14 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7503752 Medline TA: Br J Obstet Gynaecol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 944-7 Citation Subset: AIM; IM; J |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cholesterol / blood* Cholesterol, HDL Contraceptives, Oral, Combined / pharmacology Contraceptives, Oral, Hormonal / pharmacology Female Fumarates / pharmacology Humans Lipoproteins, HDL / blood* Mestranol / pharmacology* Norethindrone / pharmacology* Time Factors |
| Chemical | |
Reg. No./Substance:
|
0/Cholesterol, HDL; 0/Contraceptives, Oral, Combined; 0/Contraceptives, Oral, Hormonal; 0/Fumarates; 0/Lipoproteins, HDL; 110-17-8/fumaric acid; 57-88-5/Cholesterol; 68-22-4/Norethindrone; 72-33-3/Mestranol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Problems in the management of patients with artificial valves during pregnancy.
Next Document: Reliability and accuracy of the zona-free hamster ova assay in the assessment of male fertility.