Document Detail

Plasma granulocyte colony stimulating factor concentrations in pregnant women.
MedLine Citation:
PMID:  7557644     Owner:  NLM     Status:  MEDLINE    
We measured the plasma granulocyte colony stimulating factor (G-CSF) concentrations in pregnant women to evaluate the association between G-CSF and increased neutrophil counts that has been observed during pregnancy. We examined 96 pregnant and 10 nonpregnant women. The G-CSF concentrations were assayed using a sandwich enzyme immunoassay. The G-CSF concentrations in pregnant women were significantly higher at all times than those of nonpregnant women. The G-CSF concentrations were also significantly higher during than before labor. The plasma G-CSF concentrations were positively correlated with the neutrophil counts during the 3rd trimester only. In conclusion, increased G-CSF concentrations may be related to the increases in neutrophil counts in pregnant women, especially during the 3rd trimester.
N Umesaki; H Fukumasu; M Miyama; M Kawabata; S Ogita
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  40     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  1995  
Date Detail:
Created Date:  1995-10-30     Completed Date:  1995-10-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  5-7     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Osaka City University Medical School, Japan.
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MeSH Terms
Granulocyte Colony-Stimulating Factor / blood*
Immunoenzyme Techniques*
Leukocyte Count
Pregnancy / blood*
Pregnancy Trimester, Third
Reg. No./Substance:
143011-72-7/Granulocyte Colony-Stimulating Factor

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