| Plasma free fatty acid reference interval in South African neonates in the first week of life. | |
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MedLine Citation:
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PMID: 20592337 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND: Non-esterified fatty acid (NEFA) levels are an important diagnostic tool in the investigation of neonatal hypoglycaemia. NEFA reference intervals have not been reported for neonates previously. METHODS: The objective of this study was to determine an NEFA reference interval for neonates. RESULTS: Heparinized plasma obtained from 106 healthy neonates in the first week of life was analysed using the Roche "Free fatty acid, Half-micro test" kit. Results were then analysed statistically for normality (Shapiro-Wilk test) and reference interval determined non-parametrically (bootstrap method). CONCLUSIONS: NEFA levels displayed a non-Gaussian distribution and the reference interval (2.5th and 97.5th percentiles) was 0.2-1.5 mmol/L (90% confidence intervals 0.1-0.3 and 1.4-2.0 mmol/L, respectively). The NEFA reference interval in South African neonates less than a week old is similar to that described in infants (1-12 months), indicating that this reference range can be used over the entire neonatal period. |
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Authors:
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F Omar; G van der Watt; V November; T S Pillay |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Annals of clinical biochemistry Volume: 47 ISSN: 1758-1001 ISO Abbreviation: Ann. Clin. Biochem. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0324055 Medline TA: Ann Clin Biochem Country: England |
Other Details:
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Languages: eng Pagination: 381-2 Citation Subset: IM |
Affiliation:
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Department of Clinical Laboratory Sciences, Division of Chemical Pathology, University of Cape Town and National Health Laboratory Service, Groote Schuur & Red Cross Children's Hospital, Cape Town, South Africa. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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