Document Detail


Plasma fibronectin in acute myeloid leukaemia.
MedLine Citation:
PMID:  3863235     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 13 patients with acute myeloid leukaemia (AML), plasma fibronectin (P-FN) was measured before, during and after chemotherapy. Pre-treatment concentrations of P-FN were within the reference range and significantly higher than the nadir value (p less than 0.05). A rise in body temperature by more than 1 degree C induced a significant fall in P-FN (p less than 0.05) and transfusion with freshly drawn blood products could prevent this fall. P-FN concentrations were significantly higher in patients obtaining complete haematological remission than in patients in whom remission could not be induced (p less than 0.001). This difference could not be attributed to transfusion or febrile episodes.
Authors:
E L Petersen; T Orntoft; J H Jensen; H K Nielsen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of haematology     Volume:  35     ISSN:  0036-553X     ISO Abbreviation:  Scand J Haematol     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-11-20     Completed Date:  1985-11-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0404507     Medline TA:  Scand J Haematol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  225-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Transfusion
Cytarabine / therapeutic use
Daunorubicin / therapeutic use
Female
Fibronectins / blood*
Humans
Leukemia, Myeloid, Acute / blood*,  drug therapy
Male
Middle Aged
Precipitin Tests
Thioguanine / therapeutic use
Chemical
Reg. No./Substance:
0/Fibronectins; 147-94-4/Cytarabine; 154-42-7/Thioguanine; 20830-81-3/Daunorubicin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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