Document Detail

Plasma fibronectin concentrations in breast fed and formula fed neonates.
MedLine Citation:
PMID:  3389869     Owner:  NLM     Status:  MEDLINE    
Plasma fibronectin concentration was measured in neonates of 2 to 5 days of age. Although breast fed and formula fed infants were similar in demographic characteristics, the mean (SD) plasma concentration of fibronectin in 26 breast fed infants, 237 (117) mg/l, was significantly higher than in 27 formula fed infants (171 (91) mg/l). Fibronectin was detected in five colostrum specimens (mean concentration 13.4 mg/l). Similar bands were detected after gel electrophoresis of purified adult plasma fibronectin and whole plasma from breast fed and formula fed neonates after staining or immunoblotting. Fibronectin isolated from breast milk also appeared similar to purified plasma fibronectin. It is possible, although unlikely, that fibronectin is absorbed intact from ingested colostrum. Alternatively, a factor(s) might be present in colostrum that contributes to the regulation of plasma fibronectin concentration.
H E Friss; L G Rubin; S Carsons; J Baranowski; P J Lipsitz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  63     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-08-11     Completed Date:  1988-08-11     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  528-32     Citation Subset:  AIM; IM    
Department of Pediatrics, Schneider Children's Hospital, New York.
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MeSH Terms
Bottle Feeding*
Breast Feeding*
Colostrum / analysis
Fibronectins / blood*
Infant Food / analysis
Infant, Newborn
Milk, Human / analysis
Reg. No./Substance:

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