| Plasma exchange in patients with toxic epidermal necrolysis. | |
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MedLine Citation:
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PMID: 12109948 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe our experience with plasma exchange (PE) therapy in 13 patients with drug-induced toxic epidermal necrolysis (TEN), 4 of whom had malignant disorders. Skin lesions covered 17% to 100% of total body surface area and 1 to 4 mucous membranes were involved. None of the patients was hospitalized in a burn unit. The patients underwent from 2 to 5 PE sessions (mean 3.4 +/- 0.2 standard error of mean [SEM], median 3) exchanging 6.6 to 17.6 L of plasma (mean 10.1 +/- 0.7 SEM, median 10). PE sessions were carried out every other day in 8 patients and daily in 5. Three patients died (23%) while the remaining 10 (77%) had a full recovery. Plasmapheresis may be an effective treatment in patients with drug-induced TEN hospitalized outside a burn unit. |
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Authors:
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Gerasimos Bamichas; Taisir Natse; Fotini Christidou; Maria Stangou; Anna Karagianni; Sotiris Koukourikos; Georgios Chaidemenos; Fotis Chrysomallis; Kostas Sombolos |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis Volume: 6 ISSN: 1091-6660 ISO Abbreviation: Ther Apher Publication Date: 2002 Jun |
Date Detail:
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Created Date: 2002-07-11 Completed Date: 2002-08-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9706703 Medline TA: Ther Apher Country: United States |
Other Details:
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Languages: eng Pagination: 225-8 Citation Subset: IM |
Affiliation:
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Renal Unit, General Hospital G. Papanikolaou, Aristotele University of Thessaloniki, Greece. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Epidermal Necrolysis, Toxic / therapy* Female Humans Male Middle Aged Plasma Exchange* Retrospective Studies Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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