Document Detail

Plasma exchange as treatment for Lawsone (henna) intoxication.
MedLine Citation:
PMID:  17385718     Owner:  NLM     Status:  MEDLINE    
Lawsone (2-hydroxy-1,4-naphthoquinone) is the active ingredient of Lawsonia alba, whose crushed leaves are known as henna, used as a hair and skin dye in many parts of the world. Accidental or deliberate ingestion of Lawsone has a high mortality rate (up to 31%) owing to rhabdomyolysis and renal failure. The authors report the first successful use of plasmapheresis as an adjunct to the treatment of these symptoms in a 69-year-old man who suffered severe symptoms of Lawsone poisoning due to inadvertent ingestion. Although most cases reported in the literature have been treated using supportive techniques, including hemodialysis, the high mortality despite these measures suggests that prompt plasma exchange may be a lifesaving technique for this syndrome.
Deborah Rund; Tova Schaap; Nael Da'as; Dina Ben Yehuda; Joseph Kalish
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical apheresis     Volume:  22     ISSN:  0733-2459     ISO Abbreviation:  J Clin Apher     Publication Date:  2007  
Date Detail:
Created Date:  2007-07-30     Completed Date:  2007-10-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8216305     Medline TA:  J Clin Apher     Country:  United States    
Other Details:
Languages:  eng     Pagination:  243-5     Citation Subset:  IM    
Copyright Information:
(c) 2007 Wiley-Liss, Inc.
Plasmapheresis Unit, Department of Hematology, Hadassah University Hospital, Ein Kerem, Jerusalem, Israel.
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MeSH Terms
Hair Dyes / poisoning*
Naphthoquinones / poisoning*
Plasma Exchange*
Treatment Outcome
Reg. No./Substance:
0/Hair Dyes; 0/Naphthoquinones; 83-72-7/lawsone

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