| Plasma estradiol-17 beta concentrations in the cow during induced estrus and after injection of estradiol-17 beta benzoate and estradiol-17 beta cypionate--a preliminary study. | |
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MedLine Citation:
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PMID: 2319634 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Plasma estradiol-17 beta concentrations were investigated in cows during induced estrus and after an intramuscular injection of 10 mg of estradiol-17 beta benzoate and estradiol-17 beta cypionate to determine a withdrawal period for both preparations. After the estradiol-17 beta benzoate injection, the plasma estradiol-17 beta concentration was higher than the physiological maximum of 24 pg/ml obtained during induced estrus for a period of 114 +/- 10 h (mean +/- SEM). For estradiol-17 beta cypionate the corresponding value was 170 +/- 17 h (mean +/- SEM). A withdrawal period of 7 days for the benzoate ester and of 10 days for estradiol-17 beta cypionate is therefore proposed. These results were confirmed by biopsies taken at the injection site 8 and 15 days after the injection of estradiol-17 beta benzoate and estradiol-17 beta cypionate, respectively. In these biopsies no residues of estradiol-17 beta nor of its esters could be detected. |
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Authors:
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L Vynckier; M Debackere; A De Kruif; M Coryn |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of veterinary pharmacology and therapeutics Volume: 13 ISSN: 0140-7783 ISO Abbreviation: J. Vet. Pharmacol. Ther. Publication Date: 1990 Mar |
Date Detail:
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Created Date: 1990-05-10 Completed Date: 1990-05-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7910920 Medline TA: J Vet Pharmacol Ther Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 36-42 Citation Subset: IM |
Affiliation:
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Laboratory of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, R.U.G., Gent, Belgium. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cattle / blood* Estradiol / administration & dosage, analogs & derivatives*, blood*, metabolism Estrus / blood* Female Injections, Intramuscular / veterinary Time Factors |
| Chemical | |
Reg. No./Substance:
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313-06-4/estradiol 17 beta-cypionate; 50-28-2/Estradiol; 983-30-2/estradiol-17 beta-benzoate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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