| Plasma nitrite/nitrate and erythropoietin levels in cross-country skiers during altitude training. | |
| | |
MedLine Citation:
|
PMID: 12032406 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The aim of this study was to evaluate the effects of training at altitude on plasma nitrite/nitrate and erythropoietin levels since previously it has been reported an interaction of the NO/cGMP system in erythropoietin production. METHODS: Nine physically trained cross-country male skiers, usually living at 800-1200 m altitude, underwent 6 days of intensive training at a moderate altitude of 3100 m preceeded by 2 days of acclimatisation. Six team-managers, selected as controls, did not undergo any regular physical activity in the last 5 years and during the altitude period. Haematological parameters, erythropoietin and nitrite/nitrate were measured prior to reach the place at altitude, at the end of the period at moderate altitude and 7 days after returning at home. RESULTS: Haematocrit significantly increased in controls after 8 days at altitude. Erythropoietin levels significantly increased after the intensive altitude training only in trained subjects (13.1+/-1.7 vs 6.7+/-1.7 mU x ml-1, p<0.001). Nitrite/nitrate baseline values were significantly higher in trained subjects compared to untrained (49.9+/-17.9 vs 25.4+/-2.8 micromol x l(-1), p<0.01); the altitude period significantly increased nitrite/nitrate levels, in untrained subjects, to the same values observed in trained subjects under control conditions (47.0+/-10.3 micromol x l(-1)). CONCLUSIONS: In our experimental conditions we demonstrated the influence of hypoxia on Epo levels in athletes sustaining a short-term training and the role of a regular physical activity (partly independent from altitude hypoxia) on NO production. |
| | |
Authors:
|
F Schena; L Cuzzolin; L Rossi; M Pasetto; G Benoni |
Related Documents
:
|
12215956 - Red blood cell profile of elite olympic distance triathletes. a three-year follow-up. 2317176 - Altitude symptomatology and mood states during a climb to 3,630 meters. 3023276 - Propranolol does not impair exercise oxygen uptake in normal men at high altitude. 8514706 - Effects of chronic hypoxia and exercise on plasma erythropoietin in high-altitude resid... 11693746 - Real-time assessment of myocardial perfusion and wall motion during bicycle and treadmi... 12563216 - Effect of elastic compression stockings on venous hemodynamics during walking. |
Publication Detail:
|
Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
|
Title: The Journal of sports medicine and physical fitness Volume: 42 ISSN: 0022-4707 ISO Abbreviation: J Sports Med Phys Fitness Publication Date: 2002 Jun |
Date Detail:
|
Created Date: 2002-05-28 Completed Date: 2002-10-16 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0376337 Medline TA: J Sports Med Phys Fitness Country: Italy |
Other Details:
|
Languages: eng Pagination: 129-34 Citation Subset: IM |
Affiliation:
|
Ce.Bi.S.M., Center of Bioengineering and Motor Sciences, Rovereto (TN), Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Altitude* Analysis of Variance Anoxia / blood Erythropoiesis / physiology* Hematocrit Humans Male Nitric Oxide / blood* Physical Fitness / physiology* Skiing* |
| Chemical | |
Reg. No./Substance:
|
10102-43-9/Nitric Oxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Distal deep venous thrombosis in a hemophilia A patient with inhibitor and severe infectious disease...
Next Document: Attainment of maximal exercise criteria in boys and men.