| Plasma endothelin-1 levels in patients with aldosterone-producing adenoma and pheochromocytoma. | |
| | |
MedLine Citation:
|
PMID: 8886476 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The aim of the study was to evaluate possible changes of plasma endothelin-1 levels (ET-1) in patients with hypertension secondary to primary aldosteronism and pheochromocytoma. We enrolled in the study: 12 patients affected by aldosterone-producing adenoma (5 M and 7 W; mean age 42.1 +/- 17.2 years); 8 patients with pheochromocytoma (5 M, 3 W; mean age 36.2 +/- 17.1 years); 15 patients with essential hypertension (9 M, 6 W; mean age 48.5 +/- 10 years). We also enrolled a normal control group (8 M, 12 W; mean age 34.2 +/- 11 years). The mean plasma ET-1 concentrations in patients with pheochromocytoma were significantly higher (23.9 +/- 5.2 pg/ml) than those in normal subjects (7.3 +/- 1.9 pg/ml), in patients with primary aldosteronism (12.1 +/- 3.8 pg/ml) and in patients with essential hypertension (9.2 +/- 3 pg/ml); p < 0.001, respectively. The present investigation demonstrates that in human adrenal hypertension patients with pheochromocytoma have increased circulating ET-1 levels respect to patients with aldosterone-producing adenoma. |
| | |
Authors:
|
C Letizia; G De Toma; S Cerci; L Scuro; A De Ciocchis; C D'Ambrosio; R Massa; A Cavallaro; D Scavo |
Related Documents
:
|
17587926 - Scorpion sting sydrome - a ten year experience. 7601086 - The efficacy of isradipine in uncontrolled hypertension in ethiopian patients. 16932426 - Primary aldosteronism: diagnostic and treatment strategies. 15033256 - Clinical and haemodynamic effects of sildenafil in pulmonary hypertension: acute and mi... 19632526 - Quantitative assessment of cibenzoline administration for vagally mediated paroxysmal a... 6588396 - Mood-incongruent versus mood-congruent psychosis: differential antipsychotic response t... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Clinical and experimental hypertension (New York, N.Y. : 1993) Volume: 18 ISSN: 1064-1963 ISO Abbreviation: Clin. Exp. Hypertens. Publication Date: 1996 Oct |
Date Detail:
|
Created Date: 1997-02-03 Completed Date: 1997-02-03 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9305929 Medline TA: Clin Exp Hypertens Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 921-31 Citation Subset: IM |
Affiliation:
|
I Patologia Medica, University of Rome La Sapienza, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenoma
/
blood*,
complications Adrenal Gland Neoplasms / blood*, complications Adult Biological Markers Endothelin-1 / blood* Female Humans Hyperaldosteronism / blood*, etiology Hypertension / blood*, etiology Male Middle Aged Pheochromocytoma / blood*, complications |
| Chemical | |
Reg. No./Substance:
|
0/Biological Markers; 0/Endothelin-1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cardiovascular characteristics in normotensive subjects with or without family history of hypertensi...
Next Document: Role of the circulating renin-angiotensin system in the pathogenesis of hypertension in transgenic r...