Document Detail


Plasma cytokine levels in patients with severe burn injury--with reference to the relationship between infection and prognosis.
MedLine Citation:
PMID:  8982534     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Blood levels of various cytokines were determined in patients with burn injury immediately after the accident, and the relationship between cytokines and morbid condition was investigated. There was almost no marked elevation of cytokines in the early stage of burn injury. Throughout the entire course, tumour necrosis factor alpha, interleukin 6 and interleukin 8, as cytokines, showed high levels in patients with burn injury associated with sepsis and those who died. These levels well reflected the severity in the phase complicated with sepsis.
Authors:
Y Yamada; S Endo; K Inada
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Burns : journal of the International Society for Burn Injuries     Volume:  22     ISSN:  0305-4179     ISO Abbreviation:  Burns     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-03-18     Completed Date:  1997-03-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8913178     Medline TA:  Burns     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  587-93     Citation Subset:  IM    
Affiliation:
Critical Care and Emergency Center, Iwate Medical University, Morioka, Japan.
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MeSH Terms
Descriptor/Qualifier:
Accidents
Adult
Aged
Body Surface Area
Body Temperature
Burns / blood*,  complications,  pathology
Cytokines / blood*
Female
Humans
Interleukin-6 / blood
Interleukin-8 / blood
Leukocyte Count
Male
Middle Aged
Prognosis
Sepsis / blood,  complications*
Survival Rate
Tumor Necrosis Factor-alpha / analysis
Wound Infection / complications
Chemical
Reg. No./Substance:
0/Cytokines; 0/Interleukin-6; 0/Interleukin-8; 0/Tumor Necrosis Factor-alpha

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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