Document Detail


Plasma cortisol studies with 0.05% halometasone cream and ointment in patients with psoriasis.
MedLine Citation:
PMID:  6832467     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Plasma cortisol levels were determined by a radioimmunological assay in three groups of ten psoriasis patients treated with 0.05% halometasone ointment, 0.05% halometasone cream and 0.025% fluocinolone acetonide ointment, without occlusive dressings, for 7 days. Fourteen grams of the corticoid topical was applied daily (7 g/b.i.d.) to the psoriasis plaques covering an average of 25% of the body surface. No significant differences with respect to plasma cortisol values at 8 a.m. before, during and after treatment were evident in any of the three treatment groups, nor did the treatment groups significantly differ from one another with regard to their effect on the plasma cortisol levels. No side-effects were observed.
Authors:
C Tomasini; G Castiglioni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of international medical research     Volume:  11 Suppl 1     ISSN:  0300-0605     ISO Abbreviation:  J. Int. Med. Res.     Publication Date:  1983  
Date Detail:
Created Date:  1983-05-05     Completed Date:  1983-05-05     Revised Date:  2005-08-23    
Medline Journal Info:
Nlm Unique ID:  0346411     Medline TA:  J Int Med Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  38-42     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Adolescent
Adult
Aged
Anti-Inflammatory Agents / administration & dosage*,  pharmacology
Betamethasone / administration & dosage,  adverse effects,  analogs & derivatives*
Female
Humans
Hydrocortisone / blood*
Male
Middle Aged
Ointments
Psoriasis / blood,  drug therapy*
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Ointments; 378-44-9/Betamethasone; 50-23-7/Hydrocortisone; 50629-82-8/halometasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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