| Plasma concentrations of hormones and metabolic substrates in growing pigs after bovine growth hormone injections under various nutritional conditions. | |
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MedLine Citation:
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PMID: 8930522 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of GH injections on the concentrations of plasma hormones and metabolic substrates in pigs were studied under various nutritional conditions. In experiment 1, four pigs (Large white, barrows, 108 days old) were maintained at three feeding levels: (1) high level (8,501 +/- 46 kcal/ day), (2) maintenance level (2,104 +/- 44 kcal/day), and (3) fasting (last meal was on day -2). The bovine GH (100 micrograms/kg BW) was subcutaneously injected on experiment days 0, 1, and 2. In experiment 2, four pigs (Landrase, barrows, 120 days old) were maintained at the high feeding level and the bovine GH (100 micrograms/kg BW) was injected 2, 26, and 50 h after the last meal. The plasma hormone and metabolic substrate concentrations were measured. In experiment 1, the plasma IGF-I concentrations increased on days 1-4 in the high feeding level and maintenance fed pigs, but did not increase in the fasting pigs. The plasma glucose concentrations increased after the GH injection in the high feeding level and maintenance fed animals. The plasma NEFA concentrations increased after the GH injection in the maintenance fed and fasting animals. In experiment 2, the plasma IGF-I gradually decreased after the last meal. The GH injection administered 26 or 50 h after the last meal still produced an increase in the plasma IGF-I levels. These data clearly show that the effect of GH was modified depending on the nutritional condition of the pigs. |
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Authors:
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A Ozawa; K Hodate; T Johke |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Endocrine journal Volume: 43 ISSN: 0918-8959 ISO Abbreviation: Endocr. J. Publication Date: 1996 Aug |
Date Detail:
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Created Date: 1997-02-20 Completed Date: 1997-02-20 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9313485 Medline TA: Endocr J Country: JAPAN |
Other Details:
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Languages: eng Pagination: 357-62 Citation Subset: IM |
Affiliation:
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National Institute of Animal Industry, Ibaraki, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animal Nutritional Physiological Phenomena* Animals Blood Glucose / metabolism Cattle Fatty Acids, Nonesterified / blood Growth Hormone / blood, pharmacology* Hormones / blood* Insulin / blood Insulin-Like Growth Factor I / metabolism* Nutritional Status Swine / blood*, growth & development* Thyroxine / blood Triiodothyronine / blood |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Fatty Acids, Nonesterified; 0/Hormones; 11061-68-0/Insulin; 67763-96-6/Insulin-Like Growth Factor I; 6893-02-3/Triiodothyronine; 7488-70-2/Thyroxine; 9002-72-6/Growth Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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