| Plasma concentrations of free amino acids during 3 weeks treatment of massively obese children with a very low calorie diet. | |
| | |
MedLine Citation:
|
PMID: 2606127 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Eight grossly obese children (2 girls, 8 boys, age 12.6 +/- 2.1 mean +/- SD years, mean overweight 73.3 +/- 14%) were treated for 3 weeks with a very low calorie diet (VLCD), containing 1022 kJ/240 kcal, 33 g protein, 25.5 g carbohydrate and 0.7 g fat/day. Mean weight loss after 3 weeks was 9.47 +/- 2.8 kg and mean nitrogen loss was calculated to be 113.3 +/- 71.2 g. While serum electrolytes, enzymes, glucose, urea and creatinine remained almost unchanged, distinct alterations of 23 free amino acids in plasma could be observed. A transient increase of plasma valine, leucine, isoleucine and alpha-aminobutyrate during the 1st week was followed by a constant fall in the 2nd and 3rd week. Glycine, proline, serine and threonine showed a progressive increase, while cystine, histidine and, above all, alanine decreased, the diminution of alanine being most rapid during the 1st week. No significant changes were observed in plasma concentrations of arginine, asparagine, aspartic acid, citrulline, glutamic acid, glutamine, lysine, tyrosine, ornithine, phenylalanine and taurine. Total plasma amino acid content did not change during diet compared to the pre-diet period. The behavior of plasma amino acids shows a typical pattern within four groups, reflecting various interorgan substrate fluxes during hypocaloric dieting. |
| | |
Authors:
|
K Widhalm; K Zwiauer; M Hayde; E Roth |
Related Documents
:
|
6868077 - Dietary therapy in a girl with propionic acidemia: supplement with leucine resulted in ... 19052897 - Effect of dietary lysine to crude protein ratio on performance of male ross 308 broiler... 11011007 - Effects of threonine injections in the lateral hypothalamus on intake of amino acid imb... 19814847 - Identification and metabolite profiling of sitophilus oryzae l. by 1d and 2d nmr spectr... 22435477 - Identification of marker genes for lipid-lowering effect of a short-chain fructooligosa... 10797147 - Endocrine markers of semistarvation in healthy lean men in a multistressor environment. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: European journal of pediatrics Volume: 149 ISSN: 0340-6199 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 1989 Oct |
Date Detail:
|
Created Date: 1990-02-15 Completed Date: 1990-02-15 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: GERMANY, WEST |
Other Details:
|
Languages: eng Pagination: 43-7 Citation Subset: IM |
Affiliation:
|
Department of Paediatrics, University of Vienna, Austria. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Amino Acids / blood* Child Diet, Reducing* Energy Intake Female Humans Male Obesity, Morbid / blood, diet therapy* |
| Chemical | |
Reg. No./Substance:
|
0/Amino Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Hyperprolinaemia type I and white matter disease: coincidence or causal relationship?
Next Document: Glycogen storage disease, Fanconi nephropathy, abnormal galactose metabolism and mitochondrial myopa...