| Plasma cholinesterase and trophoblastic disease. Gestational trophoblastic disease and reduced activity of plasma cholinesterase. | |
| | |
MedLine Citation:
|
PMID: 6314838 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A case of prolonged action of suxamethonium in a patient with gestational trophoblastic disease is reported. Postoperatively the patient was found to have markedly reduced plasma cholinesterase activity (363 IU/litre) with a normal cholinesterase phenotype. Consequently plasma cholinesterase activity and phenotype were measured in six other patients with the condition and these results compared with those of 22 patients with normal first trimester pregnancies undergoing therapeutic abortion. Plasma cholinesterase phenotype was normal in all patients studied. The activity was significantly decreased (p less than 0.05) from the normal range (620-1370 IU/litre) in all patients with trophoblastic disease. In the 22 patients with normal pregnancies, 14 had activity values in the abnormal range (less than 620 IU/litre) while the mean cholinesterase activity of the group as a whole was significantly decreased (561.8 IU/litre, p less than 0.05) below the normal range. These results confirm the presence of a decrease in plasma cholinesterase activity in early pregnancy and provide new evidence for a decrease in activity in a pseudopregnancy state. |
| | |
Authors:
|
J M Davies; D Carmichael; C Dymond |
Related Documents
:
|
6403138 - Treatment of haemophilia and related disorders in britain and northern ireland during 1... 21264488 - Postmarketing surveillance of safety and effectiveness of etanercept in japanese patien... 19538758 - Plasma fibrinolysis is related to the degree of organ dysfunction but not to the concen... 324348 - Modification of functional serum antithrombin iii assay for fibrometer. results of exam... 2017898 - Changes in absolute power values of eeg spectra in the follow-up of alzheimer's disease. 21461048 - Legionnaires' disease with facial nerve palsy. |
Publication Detail:
|
Type: Case Reports; Comparative Study; Journal Article |
Journal Detail:
|
Title: Anaesthesia Volume: 38 ISSN: 0003-2409 ISO Abbreviation: Anaesthesia Publication Date: 1983 Nov |
Date Detail:
|
Created Date: 1983-12-21 Completed Date: 1983-12-21 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0370524 Medline TA: Anaesthesia Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 1071-4 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cholinesterases / blood*, genetics Female Humans Phenotype Pregnancy Succinylcholine / adverse effects Trophoblastic Neoplasms / enzymology*, surgery Uterine Neoplasms / enzymology*, surgery |
| Chemical | |
Reg. No./Substance:
|
306-40-1/Succinylcholine; EC 3.1.1.8/Cholinesterases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Adrenal suppression following extradural steroids.
Next Document: Preparation and stabilization of aqueous/ethanolic superoxide solutions.