Document Detail

Plasma cell granuloma of the thyroid: a conservative approach to a rare condition and review of the literature.
MedLine Citation:
PMID:  21048843     Owner:  NLM     Status:  In-Data-Review    
Introduction. We present a case of an 89-year-old female who attended our surgical endocrine clinic with a 3-month history of a left-sided neck lump. There was no past medical history of thyroid disease. Methods. Following examination and further investigation, including core biopsy, a diagnosis of plasma cell granuloma of the thyroid was made. Biochemical testing of thyroid function and Thyroid Peroxidase Antibody was in-keeping with an associated Hashimoto's thyroiditis. Results. The patient was treated conservatively with thyroxine and regularly seen in clinic. TSH levels improved and the lump showed signs of regression. Conclusion. Plasma cell granuloma of the thyroid is rare with only 16 previously reported cases. We present a new approach to management without the use of surgery or steroids. The literature is reviewed comparing clinico-pathological features and management of other reported cases.
W A Barber; M Fernando; D R Chadwick
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Publication Detail:
Type:  Journal Article     Date:  2010-02-07
Journal Detail:
Title:  Journal of thyroid research     Volume:  2010     ISSN:  2042-0072     ISO Abbreviation:  J Thyroid Res     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101536655     Medline TA:  J Thyroid Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  840469     Citation Subset:  -    
Department of General Surgery, Chesterfield Royal Hospital, Calow, Chesterfield S44 5BL, UK.
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