Document Detail


Plasma catecholamine responses to dynamic exercise in patients with coronary artery disease--the relationship between sympathetic activity and systolic blood pressure and exercise-induced ventricular arrhythmias.
MedLine Citation:
PMID:  1453536     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to investigate the relationship between sympathetic activity and postexercise systolic blood pressure (SBP) and exercise-induced ventricular arrhythmias in patients with coronary artery disease (CAD), we studied 38 patients and 9 normal subjects who underwent treadmill testing. Peak pressure-rate product was similar in the 2 groups. The plasma concentrations of norepinephrine and epinephrine at rest and immediately after exercise were significantly higher in patients with CAD compared with normal subjects (norepinephrine at rest, p < 0.01; norepinephrine immediately after exercise, p < 0.05; epinephrine at rest, p < 0.05; epinephrine immediately after exercise, p < 0.05). The level of norepinephrine immediately after exercise was significantly higher in 15 patients with a postexercise SBP increase than in 23 patients without that SBP change (p < 0.05), whereas the level of epinephrine was similar in the 2 groups. The level of epinephrine immediately after exercise was significantly higher in 10 patients with exercise-induced premature ventricular contractions than in 28 patients without those arrhythmias (p < 0.05), whereas the level of norepinephrine was similar in the 2 groups. We conclude that a postexercise SBP increase is related to the augmentation of sympathoneural activity and that exercise-induced ventricular arrhythmias are related to the augmentation of sympathoadrenal activity.
Authors:
H Miyakoda; N Noguchi; T Matsumoto; H Kitamura; T Kinugawa; K Ogino; A Hoshio; H Kotake; H Mashiba
Related Documents :
6731296 - Relation between electrocardiographic and scintigraphic location of myocardial ischemia...
6673826 - Systolic time-interval evaluation by thermistor plethysmography during uninterrupted dy...
15120806 - Limitation of exercise tolerance in chronic heart failure: distinct effects of left bun...
11587066 - Cholecystokinin cholescintigraphy: clinical indications and proper methodology.
20010296 - The role of exercise therapy in the management of juvenile idiopathic arthritis.
8333376 - Mr imaging as a potential diagnostic test for metabolic myopathies: importance of varia...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  56     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1992 Nov 
Date Detail:
Created Date:  1992-12-31     Completed Date:  1992-12-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1115-23     Citation Subset:  IM    
Affiliation:
First Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Arrhythmias, Cardiac / etiology*
Blood Pressure / physiology*
Coronary Disease / blood,  physiopathology*
Epinephrine / blood*
Exercise*
Exercise Test
Female
Humans
Male
Middle Aged
Norepinephrine / blood*
Sympathetic Nervous System / physiopathology*
Chemical
Reg. No./Substance:
51-41-2/Norepinephrine; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Right ventricular wall motion disturbance and determinants of the appearance of hemodynamic right ve...
Next Document:  Improvement in long-term prognosis by coronary bypass surgery in patients with 3-vessel coronary dis...