| Plasma beta-endorphin concentrations and analgesia-muscle relaxation in the newborn infant supported by mechanical ventilation. | |
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MedLine Citation:
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PMID: 8021759 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We evaluated the effects of pancuronium and opiates on plasma beta-endorphin concentrations in 25 infants supported by mechanical ventilation. Infants receiving opiate were randomly assigned to receive either fentanyl or morphine. There was no change in beta-endorphin concentrations after administration of pancuronium, whereas both fentanyl and morphine reduced beta-endorphin concentrations by approximately 60%. |
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Authors:
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S P Ionides; M G Weiss; M Angelopoulos; T F Myers; R J Handa |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: The Journal of pediatrics Volume: 125 ISSN: 0022-3476 ISO Abbreviation: J. Pediatr. Publication Date: 1994 Jul |
Date Detail:
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Created Date: 1994-07-29 Completed Date: 1994-07-29 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 113-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatrics and Cell Biology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Fentanyl / pharmacology, therapeutic use* Humans Infant, Newborn Male Morphine / pharmacology, therapeutic use* Muscle Relaxation / drug effects Pancuronium / pharmacology, therapeutic use* Prospective Studies Respiration, Artificial / adverse effects Respiratory Tract Diseases / therapy Stress, Physiological / blood, drug therapy*, etiology beta-Endorphin / blood* |
| Chemical | |
Reg. No./Substance:
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0/Pancuronium; 437-38-7/Fentanyl; 57-27-2/Morphine; 60617-12-1/beta-Endorphin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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