| Plasma androstenedione in normotensive and hypertensive pregnancy. | |
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MedLine Citation:
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PMID: 3445284 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The average plasma concentration of androstenedione (A) in 67 hypertensive pregnant women (mean 25.7 nmol/L, SD 10.0) was significantly higher (p less than 0.001) than that in 71 normotensive pregnant women (mean 14.2 nmol/L, SD 5.6). Androstenedione concentration decreased significantly (p less than 0.01) from this higher level with increasing gestation in pregnancies complicated by hypertension. In the normotensive group there was no significant correlation between androstenedione concentration and gestation, but a sharp increase in androstenedione concentration occurred prior to delivery. The androstenedione concentration in 18 hypertensive patients with fulminating disease (mean 30.7 nmol/L, SD 11.9) was significantly higher (p less than 0.02) than that in 49 hypertensive patients (mean 23.9 nmol/L, SD 8.7). The correlation between androstenedione and 19-hydroxyandrostenedione (19-OH-A) concentrations in plasma was highly significant; for 98 pairs, r = 0.43, p less than 0.001. |
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Authors:
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J D Martin; M E Hähnel; R Hähnel |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Steroids Volume: 48 ISSN: 0039-128X ISO Abbreviation: Steroids Publication Date: 1986 Nov-Dec |
Date Detail:
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Created Date: 1988-04-25 Completed Date: 1988-04-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0404536 Medline TA: Steroids Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 315-29 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, University of Western Australia, King Edward Memorial Hospital for Women, Subiaco. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Androstenedione
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blood* Estriol / blood Female Gestational Age Humans Hypertension / blood* Indicators and Reagents Infant, Newborn Pregnancy Pregnancy Complications, Cardiovascular / blood* |
| Chemical | |
Reg. No./Substance:
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0/Indicators and Reagents; 50-27-1/Estriol; 63-05-8/Androstenedione |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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