Document Detail

Plasma alkaline ribonuclease (EC and nitrogen retention in low-birth-weight infants.
MedLine Citation:
PMID:  718828     Owner:  NLM     Status:  MEDLINE    
1. Nitrogen retention was determined by classical N balance techniques in fourteen rapidly growing low-birth-weight infants receiving 3 g protein/kg body-weight and during their 3rd week of life. This was compared with plasma free alkaline ribonuclease (EC 3.I.4.22; RNase) activity and other biochemical measurements of protein nutrition. 2. Plasma RNase showed a significant positive correlation with N retention and a corresponding negative correlation with urine urea-N. These results were unexpected and suggest a different relationship between RNase and N retention in infants compared with that found by other workers in children and adults. 3. The most likely explanation of this apparent anomaly is that in all instances high activities of plasma RNase are associated with a need to conserve N. In the infants studied this may indicate some measure of 'protein economy' and they could therefore benefit from a higher protein intake.
P H Scott; H M Berger; C Kenward; P Scott; B A Wharton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of nutrition     Volume:  40     ISSN:  0007-1145     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  1978 Nov 
Date Detail:
Created Date:  1979-02-23     Completed Date:  1979-02-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  459-64     Citation Subset:  IM    
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MeSH Terms
Body Weight
Infant, Low Birth Weight*
Infant, Newborn
Nitrogen / metabolism*
Ribonucleases / blood*
Urea / urine
Reg. No./Substance:
57-13-6/Urea; 7727-37-9/Nitrogen; EC 3.1.-/Ribonucleases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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