Document Detail


Plasma visfatin is increased after high-intensity exercise.
MedLine Citation:
PMID:  20606422     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND/AIMS: Visfatin is a newly characterized protein that is highly expressed in visceral adipose tissue and may play a role in insulin resistance. We investigated the effects of repeated short bouts of high-intensity exercise on plasma visfatin and related metabolic responses.
METHODS: Six young, physically fit men (22.8 +/- 2.3 years; 78.5 +/- 2.3 kg; and body mass index 22.1 +/- 1.2) performed a single session of a running-based anaerobic sprint exercise (7 sets of 6 x 35 m every 10 s, with 1 min rest between sets). Venous blood samples were collected before, immediately after, and 45 and 90 min after exercise to assess plasma visfatin, insulin, glucose, lactate and glutathione responses.
RESULTS: After adjustment for postexercise changes in plasma volume, the data indicate a significant increase in plasma visfatin (12.5 +/- 2.0 vs. 26.6 +/- 3.9 ng/ml, p < 0.02), insulin (p < 0.05), and glucose (p < 0.002) concentrations, and homeostasis model assessment of insulin resistance (p < 0.02), immediately after the exercise session. At 45 min of recovery, all metabolic measures, with the exception of lactate, had returned to baseline levels.
CONCLUSION: The elevation in plasma visfatin, together with increased plasma glucose and insulin concentrations immediately after high-intensity exercise, may sensitize tissues for postexercise glucose uptake and glycogen restoration. Our results also support a temporary and early postexercise anorexigenic metabolic state.
Authors:
Abbass Ghanbari-Niaki; Marziyeh Saghebjoo; Raheleh Soltani; John P Kirwan
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-07-02
Journal Detail:
Title:  Annals of nutrition & metabolism     Volume:  57     ISSN:  1421-9697     ISO Abbreviation:  Ann. Nutr. Metab.     Publication Date:  2010  
Date Detail:
Created Date:  2010-08-27     Completed Date:  2010-11-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8105511     Medline TA:  Ann Nutr Metab     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  3-8     Citation Subset:  IM    
Copyright Information:
2010 S. Karger AG, Basel.
Affiliation:
University of Mazandaran, Babolsar, Iran.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Glucose / metabolism
Body Mass Index
Exercise*
Exercise Test
Glycogen / metabolism
Humans
Insulin* / blood,  secretion
Insulin Resistance
Intra-Abdominal Fat
Male
Nicotinamide Phosphoribosyltransferase / blood*,  metabolism
Chemical
Reg. No./Substance:
0/Blood Glucose; 11061-68-0/Insulin; 9005-79-2/Glycogen; EC 2.4.2.12/Nicotinamide Phosphoribosyltransferase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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