| Plasma plasminogen activator inhibitor 1 (PAI-1) and P-selectin levels in urgent hypertension: effect of single dose captopril and nifedipine on fibrinolytic activity. | |
| | |
MedLine Citation:
|
PMID: 21028997 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
In this study, we primarily aimed to identify the acute effects of hypertension on fibrinolytic function in previously untreated urgent hypertensive patients and to evaluate the influence of two commonly used, short-acting, anti-hypertensive agents, captopril and nifedipine, in these patients. Patient groups were selected homogeneously, i.e., only previously untreated patients amidst an urgent hypertensive episode and having no co-morbid disease were included-and randomly assigned to receive either captopril or nifedipine for immediate management. These two treatment groups were matched for age, gender, and mean arterial blood pressure. Study results demonstrated that lowering blood pressure with either agent improved fibrinolytic function; however, in those patients given captopril, this beneficial effect was more prominent, providing evidence supporting the preferential use of short-acting, angiotensin-converting enzyme (ACE) inhibitors in this setting. |
| | |
Authors:
|
Ozlem Tiryaki; Hakan Buyukhatipoglu; Celalettin Usalan |
Related Documents
:
|
1480537 - Absence of potentiation of the skin response to intradermal bradykinin by a long-acting... 2684367 - The effect of intravenous captopril on the left ventricular function-an acute study by ... 7041587 - Hemodynamic effects of captopril in patients with severe chronic heart failure. 2045137 - Prevention of cold-induced increase in blood pressure of rats by captopril. 21150917 - Institutional hypertension control in malaysia: a multicenter study focusing on gender ... 17503947 - Novel liquid flow sensor based on differential pressure method. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical and experimental hypertension (New York, N.Y. : 1993) Volume: 32 ISSN: 1525-6006 ISO Abbreviation: Clin. Exp. Hypertens. Publication Date: 2010 |
Date Detail:
|
Created Date: 2010-10-29 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9305929 Medline TA: Clin Exp Hypertens Country: England |
Other Details:
|
Languages: eng Pagination: 347-51 Citation Subset: IM |
Affiliation:
|
Gaziantep University School of Medicine, Department of Nephrology, Gaziantep, Turkey. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pitavastatin further decreases serum high-sensitive C-reactive protein levels in hypertensive patien...
Next Document: Salt and nitric oxide synthase inhibition-induced hypertension: kidney dysfunction and brain anti-ox...