Document Detail

Plasma LH and androgen levels in the red-winged blackbird (Agelaius phoeniceus) treated with a potent GnRH analogue.
MedLine Citation:
PMID:  1679696     Owner:  NLM     Status:  MEDLINE    
1. Low doses of GnRH-A (0.01-0.10-1.0 micrograms) given during the annual testes growth period did not clearly affect plasma LH and androgen levels 10 min following the injection. 2. The first injection of high doses of GnRH-A (2.0-10.0-20.0 micrograms) markedly increased plasma LH and androgen levels measured 10 min following the injection. The increase in plasma LH level was dose-dependent and the maximal LH level was obtained with 10.0 micrograms of GnRH-A. 3. Impairment of the LH response to GnRH-A was assessed by comparing the first and the fourteenth injection of high doses of GnRH-A. Evidences of pituitary gland desensitization are reported since plasma LH levels were reduced following the fourteenth injection in all groups. 4. Plasma androgen levels following high doses of GnRH-A were not clearly affected in red-winged blackbirds.
D Lacombe; A Cyr; P Matton
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Comparative biochemistry and physiology. A, Comparative physiology     Volume:  99     ISSN:  0300-9629     ISO Abbreviation:  Comp Biochem Physiol A Comp Physiol     Publication Date:  1991  
Date Detail:
Created Date:  1991-10-16     Completed Date:  1991-10-16     Revised Date:  2008-10-30    
Medline Journal Info:
Nlm Unique ID:  1276312     Medline TA:  Comp Biochem Physiol A Comp Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  603-7     Citation Subset:  IM    
Raptor Research Center, McDonald College of McGill University, Ste-Anne-de-Bellevue, Qc, Canada.
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MeSH Terms
Androgens / blood*
Gonadotropin-Releasing Hormone / analogs & derivatives*,  pharmacology
Luteinizing Hormone / blood*
Testis / growth & development
Triptorelin* / analogs & derivatives*
Reg. No./Substance:
0/Androgens; 33515-09-2/Gonadotropin-Releasing Hormone; 57773-63-4/Triptorelin; 57773-65-6/Tryptal; 9002-67-9/Luteinizing Hormone

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