| Plasma Concentrations Of Pregnancy-Associated Glycoproteins Measured Using Anti-Bovine PAG-2 Antibodies On Day 120 Of Gestation Predict Abortion In Dairy Cows Naturally Infected With Neospora caninum. | |
| | |
MedLine Citation:
|
PMID: 23228018 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The present study sought to determine: (i) the effects of Neospora caninum infection and twin pregnancy on plasma pregnancy-associated glycoprotein-2 (PAG-2) concentrations throughout pregnancy and (ii) whether plasma PAG-2 concentrations could predict abortion in N. caninum-infected cows. The study was performed on a commercial Holstein-Friesian dairy herd in northeastern Spain and the final data included those recorded in 53 non-aborting and 19 aborting animals. Blood samples were collected immediately before pregnancy diagnosis (on Days 40, 90, 120, 150, 180 and 210 post-insemination) in non-aborting cows or until the time of abortion detection in aborting cows. General lineal models (GLM) repeated measures anova revealed the different behaviour of PAG-1 and PAG-2, and significant effects of Neospora seropositivity, cool season and twin pregnancy on plasma PAG-2 concentrations throughout gestation (between-subject effects). In addition, based on the odds ratios, the likelihood of abortion increased in Neospora-seropositive cows (by a factor of 7.0) compared to seronegative animals and decreased in cows with a high plasma PAG-2 concentration (>4.5 ng/ml) on Day 120 of pregnancy (by a factor of 0.24), compared to the remaining cows. In conclusion, there is a relationship between plasma PAG-2 concentrations and the risk of abortion in Neospora-infected dairy cows. Thus, plasma PAG concentrations measured using anti-boPAG-2 antiserum on Day 120 of gestation could serve as an indicator of the abortion risk in N. caninum infected animals; values <4.5 ng/ml indicating a high risk of abortion in chronically infected animals. |
| | |
Authors:
|
I García-Ispierto; S Almería; B Serrano; Nm de Sousa; Jf Beckers; F López-Gatius |
Related Documents
:
|
22934578 - Mid-pregnancy maternal leptin levels, birthweight for gestational age and preterm deliv... 10962758 - Prenatal diagnosis of qt prolongation by magnetocardiography. 12969688 - Risk of death in pregnancy achieved through oocyte donation in patients with turner syn... 1837198 - Peripartum cardiomyopathy: a case report. 22873518 - Ultrasound indicated cerclage: shirodkar vs. mcdonald. 3679218 - Pregnancy loss, infant death, and suffering: legacy of syphilis and gonorrhoea in africa. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-12-10 |
Journal Detail:
|
Title: Reproduction in domestic animals = Zuchthygiene Volume: - ISSN: 1439-0531 ISO Abbreviation: Reprod. Domest. Anim. Publication Date: 2012 Dec |
Date Detail:
|
Created Date: 2012-12-11 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9015668 Medline TA: Reprod Domest Anim Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2012 Blackwell Verlag GmbH. |
Affiliation:
|
Department of Animal Production, University of Lleida, Lleida, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Dovitinib preferentially targets endothelial cells rather than cancer cells for the inhibition of he...
Next Document: Hemicarceplex Formation With a Cyclotriveratrylene-Based Molecular Cage Allows Isolation of High-Pur...