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Plasma C-reactive protein is not related to sinus non-conversion by maze procedure adjunct to mitral valve surgery.
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MedLine Citation:
PMID:  22960329     Owner:  NLM     Status:  MEDLINE    
In Framingham cohort study, C-reactive protein was not associated with incident atrial fibrillation (AF) after adjustment for left atrial size. This study examined whether levels of plasma inflammatory markers would be significant risk factors for failed maze procedure for AF. This study enrolled 88 patients with mitral valve disease undergoing valve surgery (n=32, sinus control group) or concomitant maze procedure for persistent atrial fibrillation (AF) (n=56, AF group). The mean follow-up in the AF group was 55.0 ± 17.5 months. The AF and sinus control groups did not differ in preoperative levels of C-reactive protein (p=0.636). In the AF group receiving maze procedure, the sinus conversion (n=37) and non-conversion (n=19) groups did not significantly differ in preoperative levels of interleukin-6 (p=0.607) and tumor necrosis factor-α (p=0.379). In multivariate analysis after adjustment for preoperative plasma inflammatory markers, independent factors associated with sinus conversion were AF duration (p=0.003), and left atrial area (p=0.014). In conclusion, plasma inflammatory markers are not associated with sinus non-conversion by radiofrequency maze procedure.
Chien-Jen Chen; Wen-Hao Liu; Jen-Ping Chang; Wan-Chun Ho; Yung-Lung Chen; Chih-Yuan Fang; Mien-Cheng Chen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Disease markers     Volume:  33     ISSN:  1875-8630     ISO Abbreviation:  Dis. Markers     Publication Date:  2012  
Date Detail:
Created Date:  2012-10-01     Completed Date:  2013-01-29     Revised Date:  2013-12-11    
Medline Journal Info:
Nlm Unique ID:  8604127     Medline TA:  Dis Markers     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  119-26     Citation Subset:  IM    
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MeSH Terms
Atrial Fibrillation / blood,  complications,  surgery*
Biological Markers / blood
C-Reactive Protein / metabolism*
Case-Control Studies
Catheter Ablation / methods*
Heart Valve Diseases / complications,  surgery*
Inflammation / blood
Middle Aged
Mitral Valve / surgery*
Reg. No./Substance:
0/Biological Markers; 9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): Dis Markers
Journal ID (iso-abbrev): Dis. Markers
Journal ID (publisher-id): DM
ISSN: 0278-0240
ISSN: 1875-8630
Publisher: IOS Press
Article Information
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Copyright © 2012 Hindawi Publishing Corporation.
Received Day: 16 Month: 7 Year: 2012
Accepted Day: 16 Month: 7 Year: 2012
Print publication date: Year: 2012
Electronic publication date: Day: 28 Month: 9 Year: 2012
Volume: 33 Issue: 3
First Page: 119 Last Page: 126
PubMed Id: 22960329
ID: 3810696
Article Id: 429870
DOI: 10.3233/DMA-2012-0912

Plasma C-Reactive Protein Is Not Related to Sinus Non-Conversion by Maze Procedure Adjunct to Mitral Valve Surgery
Chien-Jen Chen1
Wen-Hao Liu1
Jen-Ping Chang2
Wan-Chun Ho1
Yung-Lung Chen1
Chih-Yuan Fang1
Mien-Cheng Chen1*
1Division of Cardiology and Department of Internal MedicineKaohsiungTaiwanChina
2Division of Cardiovascular SurgeryKaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiungTaiwanChina
Correspondence: *Mien-Cheng Chen:

Article Categories:
  • Other

Keywords: Atrial fibrillation, inflammation, maze procedure, mitral valve surgery.

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