Document Detail


Plaques in the descending aorta: a new risk factor for stroke? Visualization of potential embolization pathways by 4D MRI.
MedLine Citation:
PMID:  18022846     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The combination of morphologic and hemodynamic information can help in assessing the risk of embolic stroke associated with thrombi and plaques in the descending aorta. For two acute stroke patients, the determination of individual embolic pathways using flow-sensitive four-dimensional (4D) MRI are reported. 3D visualization of local flow patterns, i.e., retrograde flow channels originating at the site of the atheroma, in conjunction with exact plaque localization, suggested potential embolization of high-risk plaques in the descending aorta although they are located downstream from the supraaortic arteries. Our findings indicate that taking plaques of the descending aorta into consideration may help improve the spectrum of pathologies considered as high-risk sources for brain ischemia.
Authors:
Andreas Harloff; Christoph Strecker; Alex P Frydrychowicz; Patrick Dudler; Andreas Hetzel; Annette Geibel; Marc Kollum; Cornelius Weiller; Jürgen Hennig; Michael Markl
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  26     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-10     Completed Date:  2008-03-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1651-5     Citation Subset:  IM    
Copyright Information:
(c) 2007 Wiley-Liss, Inc.
Affiliation:
Department of Neurology and Clinical Neurophysiology, University Hospital Freiburg, Freiburg, Germany.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aorta, Thoracic*
Aortic Diseases / complications*,  physiopathology*
Atherosclerosis / complications*,  physiopathology*
Blood Flow Velocity
Cerebrovascular Circulation*
Female
Humans
Image Enhancement / methods*
Imaging, Three-Dimensional
Magnetic Resonance Imaging / methods*
Risk Factors
Stroke / etiology*,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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