Document Detail

Plaque removal efficacy of a novel tooth wipe.
MedLine Citation:
PMID:  16170975     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This study was designed to evaluate the safety and plaque removal efficacy of a tooth wipe (Oral-B Brush-Ups) using a manual toothbrush as a control. METHODOLOGY: Twenty-five healthy subjects from a general population were enrolled in this randomized, single-use, crossover study. After 23-25 hours of no oral hygiene, oral hard and soft tissues were examined, and disclosed plaque was scored using the Turesky, et al. modification of the Quigley Hein Plaque Index. Subjects used their randomly assigned product for a timed period of one minute without instruction, after which hard and soft tissues and plaque scores were reassessed. Subjects returned to the clinic after a one-week washout period, and the clinical procedures were repeated before and after use of the alternate product. All clinical measurements were made by one examiner who was masked to treatment sequence. RESULTS: Both the tooth wipe and toothbrush were found to be safe, and significantly reduced plaque levels from whole mouth, facial, and lingual surfaces (p < 0.0001). The toothbrush removed significantly greater plaque than the tooth wipe (p < 0.0001) on whole mouth surfaces (49% vs. 29%), facial surfaces (71% vs. 44%), and lingual surfaces (25% vs. 13%). CONCLUSION: The tooth wipe provides an effective method of plaque removal when tooth brushing is not practical.
C Ram Goyal; Jimmy G Qaqish; Naresh C Sharma; Paul R Warren; MaryAnn Cugini; Maureen C Thompson
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of clinical dentistry     Volume:  16     ISSN:  0895-8831     ISO Abbreviation:  J Clin Dent     Publication Date:  2005  
Date Detail:
Created Date:  2005-09-20     Completed Date:  2005-10-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8904411     Medline TA:  J Clin Dent     Country:  United States    
Other Details:
Languages:  eng     Pagination:  44-6     Citation Subset:  D    
BioSci Research Canada Ltd., Mississauga, Ontario, Canada.
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MeSH Terms
Coloring Agents / diagnostic use
Cross-Over Studies
Dental Plaque / therapy*
Dental Plaque Index
Equipment Design
Middle Aged
Oral Hygiene / instrumentation*
Single-Blind Method
Toothbrushing / instrumentation
Toothpaste / therapeutic use
Reg. No./Substance:
0/Coloring Agents; 0/Toothpaste

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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