Document Detail


Plaque echolucency is not associated with the risk of stroke in carotid stenting.
MedLine Citation:
PMID:  16888264     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND PURPOSE: Plaque characteristics are suggested to play a potentially important role as risk factors for poor outcome after carotid artery stenting (CAS). We therefore correlated objectively and subjectively determined carotid plaque morphology with neurological complications after CAS. METHODS: We enrolled 698 consecutive patients undergoing elective CAS from a prospective single-center registry database and classified the preinterventional plaque status according to gray-scale median levels and the standardized Beletsky and Gray-Weale plaque scores. Patients were followed for 30-day neurological complications. RESULTS: Neurological complications including transient ischemic attack, minor and major stroke occurred in 5.9% (41/698) of the patients. Median gray-scale median, Beletsky and Gray-Weale scores were 45 (interquartile range [IQR] 25 to 70), 3.0 (IQR 2.0 to 3.0) and 2.0 (IQR 2.0 to 3.0), respectively. None of the scores was significantly associated with adverse outcome adjusting for traditional risk factors, medication, preinterventional symptoms, degree of stenosis, contralateral occlusion and use of cerebral protection, neither with respect to all neurological complications nor with respect to stroke and death (all P>0.05). CONCLUSIONS: Plaque echolucency measured by objective and subjective grading did not identify patients with an increased risk of peri-interventional neurological events. Evaluation of plaque echolucency therefore cannot be recommended for risk stratification in CAS patients.
Authors:
Markus Reiter; Robert A Bucek; Isabella Effenberger; Johanna Boltuch; Wilfried Lang; Ramazanali Ahmadi; Erich Minar; Martin Schillinger
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2006-08-03
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  37     ISSN:  1524-4628     ISO Abbreviation:  Stroke     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-31     Completed Date:  2006-09-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2378-80     Citation Subset:  IM    
Affiliation:
Clinic for Internal Medicine II, Department of Angiology, University of Vienna, Austria. markus.reiter@meduniwien.ac.at
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MeSH Terms
Descriptor/Qualifier:
Aged
Carotid Stenosis / mortality,  therapy*,  ultrasonography*
Databases, Factual
Female
Humans
Ischemic Attack, Transient / etiology
Male
Middle Aged
Nervous System Diseases / etiology
Prospective Studies
Registries
Risk Assessment / methods,  standards
Stents / adverse effects*
Stroke / etiology*
Comments/Corrections
Comment In:
Stroke. 2007 Aug;38(8):e67; author reply e68   [PMID:  17585088 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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