Document Detail


Plant-derived alternative treatments for the aging male: facts and myths.
MedLine Citation:
PMID:  19951012     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Soy- or red clover- derived products containing isoflavones have been amply studied in climacteric and postmenopausal women, and confusing contradicting results have been published. The beneficial effects on climacteric complaints, cholesterol and the development of osteoporosis are marginally at best and there are no uterine and mammary safety studies. In males, however, isoflavones may protect the prostate to make them less prone to develop cancer. Cell biological and animal experimental data support this notion. Clinical data about possible beneficial effects on cholesterol or in the bone are largely missing. Hence, soy or red clover products containing the mild estrogenic isoflavones with a slightly higher affinity to the estrogen receptor of the beta in comparison to the alpha subtype may prove to have some beneficial effects in males.
Authors:
Wolfgang Wuttke; Hubertus Jarry; Dana Seidlova-Wuttke
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The aging male : the official journal of the International Society for the Study of the Aging Male     Volume:  13     ISSN:  1473-0790     ISO Abbreviation:  Aging Male     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-04-30     Completed Date:  2010-06-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9808210     Medline TA:  Aging Male     Country:  England    
Other Details:
Languages:  eng     Pagination:  75-81     Citation Subset:  IM    
Affiliation:
Department of Endocrinology, University Medical Center Goettingen, Germany. ufkendo@med.uni-goettingen.de <ufkendo@med.uni-goettingen.de>
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MeSH Terms
Descriptor/Qualifier:
Aging / drug effects*
Animals
Cardiovascular System / drug effects
Female
Humans
Isoflavones / pharmacology
Male
Phytotherapy*
Plant Preparations / pharmacology*,  therapeutic use
Prostate / drug effects
Prostatic Neoplasms / prevention & control
Soybeans*
Trifolium*
Chemical
Reg. No./Substance:
0/Isoflavones; 0/Plant Preparations

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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