Document Detail

Placental weight and its ratio to birth weight in normal pregnancy at Songkhlanagarind Hospital.
MedLine Citation:
PMID:  16578997     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To quantify placental weight and its ratio to birth weight in normal pregnancy; and to determine whether abnormal placental weight and its ratio are associated with poor pregnancy outcomes. DESIGN: Prospective, cross-sectional study. MATERIAL AND METHOD: From January 1st, 2004, to December 31st, 2004, placentae were obtained from 238 normal pregnancies, between the 36th-40th gestational weeks. The trimmed and drained placenta was weighed and the mean placental weight at term was defined Distribution curves for placental weight and their ratios with gestational age were constructed. The outcomes for the intrapartum and perinatal periods were compared with normal placental weight, its ratio to the group above the 90th percentile and below the 10th percentile. Fisher's Exact Test was used to analyze the data. A p value < 0.05 was considered significant. RESULTS: The placental weight increased according to the birth weight (r = 0.450, p < 0.005). The mean placental weight at 36-40 gestational age was 519 g (SD = 89.01g). The mean placental weight to birth weight ratio was 17.08%. This ratio decreased slightly with advancing gestational age. There was an association between placental weight below the 10th percentile and fetal distress (p = 0.003). Placental weight to birth weight ratio below the 10th percentile was also associated with fetal distress (p = 0.02). Placental weight above the 90th percentile was associated with newborns requiring neonatal intensive care admission (p = 0.016). CONCLUSION: The placental weight increased according to the birth weight. The placental weight to birth weight ratio decreased slightly with advancing gestational age. Abnormal placental weight and its ratio were significantly associated with some adverse pregnancy outcomes.
Manop Janthanaphan; Ounjai Kor-Anantakul; Alan Geater
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  89     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-04-03     Completed Date:  2006-04-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  130-7     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
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MeSH Terms
Apgar Score
Birth Weight*
Cohort Studies
Fetal Growth Retardation / ultrasonography*
Gestational Age
Hospitals, University
Infant, Newborn
Maternal Age
Organ Size
Placenta / growth & development*
Pregnancy Outcome*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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