Document Detail

Placental volumes measured by 3-dimensional ultrasonography in normal pregnancies from 12 to 40 weeks' gestation.
MedLine Citation:
PMID:  18946097     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to construct nomograms of placental volumes according to gestational age and estimated fetal weight.
METHODS: From March to November 2007, placental volumes were prospectively measured by ultrasonography in 295 normal pregnancies from 12 to 40 weeks' gestation and correlated with gestational age and estimated fetal weight. Inclusion criteria were healthy women, singleton pregnancies with normal fetal morphologic characteristics on ultrasonography, and confirmed gestational age by first-trimester ultrasonography.
RESULTS: The mean placental volume ranged from 83 cm(3) at 12 weeks to 427.7 cm(3) at 40 weeks. Linear regression yielded the following formula for the expected placental volumes (ePV) according to gestational age (GA): ePV (cm(3)) = -64.68 + 12.31 x GA (r = 0.572; P < .001). Placental volumes also varied according to estimated fetal weight (EFW), and the following mathematical equation was also obtained by linear regression: ePV = 94.19 + 0.09 x EFW (r = 0.505; P < 0.001).
CONCLUSIONS: Nomograms of placental volumes according to gestational age and estimated fetal weight were constructed, generating reference values.
Carla Fagundes Silva de Paula; Rodrigo Ruano; Juliana Alvares Duarte Bonini Campos; Marcelo Zugaib
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  27     ISSN:  1550-9613     ISO Abbreviation:  J Ultrasound Med     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-10-23     Completed Date:  2009-01-09     Revised Date:  2013-01-17    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1583-90     Citation Subset:  IM    
Obstetrics Department, Faculty of Medicine, Universidade de São Paulo, São Paulo-SP, Brazil.
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MeSH Terms
Fetal Weight*
Imaging, Three-Dimensional / methods*
Organ Size
Placenta / ultrasonography*
Pregnancy Complications / ultrasonography*
Pregnancy Outcome*
Pregnancy Trimester, First
Reproducibility of Results
Sensitivity and Specificity
Ultrasonography, Prenatal / methods*
Comment In:
J Ultrasound Med. 2012 Dec;31(12):2044-5; author reply 2045-6   [PMID:  23197561 ]

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