Document Detail


Placental thickness & its correlation to gestational age & foetal growth parameters- a cross sectional ultrasonographic study.
MedLine Citation:
PMID:  23373039     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The Gestational Age (GA) is frequently over or under estimated, as the conventional gestational estimation is based on the Last Menstrual Period (LMP) and on ultrasonography (USG). Many people are unaware of their LMP and irregular menstruations and USG is bound to have a bias, thereby posing difficulties in the GA estimation.
AIM: This study was aimed at estimating the (Placental Thickness) PT and at investigating the relationship between PT and the foetal growth parameters in normal singleton pregnancies.
MATERIALS AND METHODS: Two hundred eleven pregnant women were recruited in a cross sectional prospective study. The pregnancies were between 11 to 40 weeks and they were not complicated by either maternal or foetal diseases. The Biparietal Diameter (BPD), the Abdominal Circumference (AC), the Head Circumference (HC), the Femur Length (FL) and the PT were measured by USG by using a 3.5 MHz transducer.
RESULTS: The maximum mean PT in the 1st, 2nd, 3rd and the combined trimesters were 16.5 mm, 23.78 mm, 35.81 mm and 28.49 mm respectively. The correlation between PT and the other foetal parameters was investigated by Pearson's correlation analysis. The values were expressed as mean + standard deviation. The statistical tests were two-tailed, with a p value of < 0.01, which indicated the statistical significance. There was a strong positive correlation between PT and GA, with the correlation coefficient values for the 1st, 2nd and 3rd trimesters being r = 0.609, r = 0.812 and r = 0.814 respectively. There was a significant positive correlation between PT and BPD, AC, FL, ABC, HC and FW also. The mathematical relationships between PT and GA, BPD, AC, FL, ABC, HC, FW were derived by regression analysis. The regression equation which was derived was (x - 22.92) = (0.3604) (w-27.86446) + (1.0256)(y-1.1678) + (0.0015)(z-216.2841) + (0.1047) (t-43.1555) + (0.027) (u.192.79000) + (0.0042) (v-60.3725), where x = GA in weeks, w = PT in mm, y = FW in kg, z = HC in mm, t = FL in mm, u = AC in mm and v = BPD in mm.
CONCLUSION: We conclude that PT can be used as a predictor of the GA. The subnormal PT for the corresponding GA should be evaluated for any disease condition. So, the measurement of PT should therefore be carried out routinely during the obstetric USGs.
Authors:
T Karthikeyan; Ramesh Kumar Subramaniam; Wms Johnson; K Prabhu
Related Documents :
2501079 - Toxic effects of mercurials on thyroid function of the catfish, clarias batrachus (l.).
1823079 - Maternal thyroid function in early and late pregnancy.
24577279 - Placental pathology in early-onset and late-onset fetal growth restriction.
11263469 - Effects of amiodarone administration during pregnancy on neonatal thyroid function and ...
11837499 - The role of thyroid hormone in fetal neurodevelopment.
25021399 - Pfm.31 retrospective review of in-utero fetal death cases in leicester. could the use...
6832629 - Non-fatal acute fatty liver of pregnancy.
17050549 - Comparison of two fertility-sparing approaches for bilateral borderline ovarian tumours...
22889289 - Evaluation of neonatal outcomes in elective repeat cesarean delivery at term according ...
Publication Detail:
Type:  Journal Article     Date:  2012-12-15
Journal Detail:
Title:  Journal of clinical and diagnostic research : JCDR     Volume:  6     ISSN:  2249-782X     ISO Abbreviation:  J Clin Diagn Res     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2013-02-01     Completed Date:  2013-02-04     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101488993     Medline TA:  J Clin Diagn Res     Country:  India    
Other Details:
Languages:  eng     Pagination:  1732-5     Citation Subset:  -    
Affiliation:
Assistant Professor, Department of Anatomy, Sree Balaji Medical College, Bharath University , Chennai,Tamilnadu, India.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Congenital malformations in perinatal autopsies - a study of 100 cases.
Next Document:  A comparative study of efficacy and safety of azithromycin and ofloxacin in uncomplicated typhoid Fe...